Evidence map›Paper›PMID 30423200›Full record

ArticleCancer2019

Ten-year change in neighborhood socioeconomic status and colorectal cancer.

Dong Zhang, Charles E Matthews, Tiffany M Powell-Wiley, Qian Xiao

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  7. Association of neighborhood economic trajectories and risk of mortality among older adults.Archives of public health = Archives belges de sante publique · 2026
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  8. Article
  9. Residential Segregation and Colorectal Cancer Screening in the United States, 2010 to 2018.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
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  20. Developing a Socioeconomic Status Index for Chronic Disease Prevention Research in Canada.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Dong ZhangDepartment of Health and Human Physiology, University of Iowa, Iowa City, Iowa.ORCID 0000-0002-7522-9630
Charles E MatthewsDepartment of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.
Tiffany M Powell-WileyNational Heart, Lung, and Blood Institute, Bethesda, Maryland.
Qian XiaoDepartment of Health and Human Physiology, University of Iowa, Iowa City, Iowa.
University of Iowa · USNational Cancer Institute · USNational Heart Lung and Blood Institute · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
Prospective Studies of Diet and Cancer in the AARP CohortZIACP010196 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SINHA, RASHMI · 2009 to 2025
$21.0M
Intramural NIH HHS ZIA CP010196NCI NIH HHS P30 CA086862
6 · The paper itself

Abstract

backgroundA growing body of research has demonstrated that individuals who live in neighborhoods with more severe socioeconomic deprivation may have higher risks for colorectal cancer (CRC). However, previous studies have examined neighborhood socioeconomic status (SES) at only 1 point in time, and it is unclear whether changes in neighborhood SES also can influence the risks of CRC.

methodsCox regression analysis was used to examine different trajectories of change in neighborhood SES over 10 years in relation to the incidence of CRC among 266,804 participants (ages 51-70 years) in the National Institutes of Health-AARP Diet and Health Study. Eligible participants reported living in the same neighborhood at baseline (1995-1996) and from 2004 to 2006 according to a follow-up questionnaire. Changes in neighborhood SES were measured between 1990 and 2000 by SES indices derived from Census data. Neighborhoods were grouped into 4 categories based on median SES indices in 1990 and 2000 (low-low, low-high, high-low, and high-high).

resultsCompared with residents whose neighborhoods were in the higher SES group at both time points (reference category), those whose neighborhoods were consistently in the low SES group had a 7% higher risk of developing CRC (hazard ratio, 1.07; 95% confidence interval, 1.00-1.14). Moreover, the risk of CRC was 15% higher (hazard ratio, 1.15; 95% confidence interval, 1.02-1.28) for those living in neighborhoods with decreasing SES (high-low) over time.

conclusionsThe current findings suggest that exposure to consistently low SES neighborhoods and/or a decrease in neighborhood SES over a period of time may be associated with higher risks of CRC.

Indexed as

Residence CharacteristicsSocial ClassSocioeconomic FactorsAgedCohort StudiesColorectal NeoplasmsDietFemaleFollow-Up StudiesHumansIncidenceIncomeMaleMiddle AgedPrognosisRisk Factorscancer riskcolon cancerlong-term trajectoryneighborhood socioeconomic statusrectal cancer

Identifiers

PMID30423200
PMCPMC7135907
OpenAlexW2900601140

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.