Evidence map›Paper›PMID 30423194›Full record

ReviewJournal of the American Geriatrics Society2018

Update on Medication Use Quality and Safety in Older Adults, 2017.

Shelly L Gray, Zachary A Marcum, Kenneth E Schmader, Joseph T Hanlon

Abstract readReview
In one paragraph

Review in Journal of the American Geriatrics Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Shelly L GrayDepartment of Pharmacy, School of Pharmacy, University of Washington, Seattle, Washington.
Zachary A MarcumDepartment of Pharmacy, School of Pharmacy, University of Washington, Seattle, Washington.
Kenneth E SchmaderDivision of Geriatrics, Department of Medicine, School of Medicine, Duke University Medical Center, Durham, North Carolina.
Joseph T HanlonDivision of Geriatrics, Department of Medicine, School of Medicine, Pittsburgh, Pennsylvania.
University of Washington · USDuke Medical Center · USUniversity of Pittsburgh · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Sarah B. Peskoe · 2006 to 2026
$24.6M
UW Patient-Centered Outcomes Research Career Development Program K12 2014 2019K12HS022982 · AHRQ · UNIVERSITY OF WASHINGTON · PI SULLIVAN, SEAN D · 2014 to 2018
$3.8M
Improving Outcomes of UTI in LTC Facilities: The IOU StudyR18HS023779 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NACE, DAVID A. · 2015 to 2017
$1.4M
Computational modeling of gene regulatory networks in cell differentiationZ01AG000678 · NIA · NATIONAL INSTITUTE ON AGING · PI KO, MINORU · 2008 to 2008
$286k
Agency for Health Research and QualityAHRQ HHS K12 HS022982AHRQ HHS K12HS022982AHRQ HHS R18 HS023779Intramural NIH HHS Z01 AG000678National Institute on Aging (NIA), National Institutes of Health U01AG00678NIA, Duke Pepper Older Americans Independence Center P30AG028716NIA NIH HHS P30 AG024827NIA NIH HHS P30AG024827NIA NIH HHS P30 AG028716Veterans Affairs Health Services Research and Development Service Merit Awards IIR 14-306Veterans Affairs Health Services Research and Development Service Merit Awards IIR 15-115
6 · The paper itself

Abstract

Improving the quality of medication use and medication safety in older adults is an important public health priority and is of paramount importance for clinicians who care for them. We selected four important articles from 2017 that address these issues to annotate and critique, and we discuss the broader implications for optimizing medication use. A longer list of articles is given in an online appendix. The first study provides national data on the prevalence of central nervous system-active medication polypharmacy in older adults and how this has changed over a 9-year period (2004-2013). The second study characterizes prevalence of and factors associated with nonadherence to antiepileptic drugs in 36,912 older adults with epilepsy, with an emphasis on minorities. The third study describes the extent of antibiotic use in residents of 381 long-term care facilities (LTCF) in British Columbia, Canada, from 2007 to 2014. Finally, we discuss a meta-analysis of 42 studies that evaluated the prevalence of hospital admissions caused by adverse drug reactions in older adults. This article is intended to provide a narrative review of important publications on medication use quality and safety for clinicians and researchers committed to optimizing medication use in older adults. J Am Geriatr Soc 66:2254-2258, 2018.

Indexed as

Drug MonitoringDrug PrescriptionsPatient SafetyPolypharmacyAgedBritish ColumbiaDeprescriptionsDrug-Related Side Effects and Adverse ReactionsHospitalizationHumansInappropriate PrescribingMedication Adherenceadverse drug eventsdrug-related problemsinappropriate prescribingpolypharmacy

Identifiers

PMID30423194
PMCPMC6421859
OpenAlexW2901783678

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.