ArticleCritical care medicine2019
Extracorporeal Cardiopulmonary Resuscitation: One-Year Survival and Neurobehavioral Outcome Among Infants and Children With In-Hospital Cardiac Arrest.
Article in Critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- 2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 8. Pediatric advanced life support.Clinical and experimental emergency medicine · 2026Guideline
- Systematic review and meta-analysis comparing low-flow duration of extracorporeal and conventional cardiopulmonary resuscitation.Interactive cardiovascular and thoracic surgery · 2022Pooled it
- 2020 Korean Guidelines for Cardiopulmonary Resuscitation. Part 6. Pediatric basic life support.Clinical and experimental emergency medicine · 2021Guideline
- 2020 Korean Guidelines for Cardiopulmonary Resuscitation. Part 7. Pediatric advanced life support.Clinical and experimental emergency medicine · 2021Guideline
- Associations of therapeutic hypothermia with clinical outcomes in patients receiving ECPR after cardiac arrest: systematic review with meta-analysis.Scandinavian journal of trauma, resuscitation and emergency medicine · 2020Pooled it
- Acute kidney injury after in-hospital cardiac arrest.Resuscitation · 2021Trial
- Extracorporeal Membrane Oxygenation Outside the Operating Room in Neonates and Infants.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Characteristics and outcomes of pediatric extracorporeal cardiopulmonary resuscitation (E-CPR): a nationwide retrospective analysis from the French pediatric ECMO Network.Annals of intensive care · 2026Article
- Electroencephalographic Findings Add Prognostic Value to Clinical Features Associated with Mortality on Venoarterial Extracorporeal Support.Neurocritical care · 2025Observational
- Plasma brain-related biomarkers and potential therapeutic targets in pediatric ECMO.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- Standardized therapies after ECMO program (STEP); a novel approach to pediatric post-ECMO care.The journal of extra-corporeal technology · 2024Article
- Review
- CPR quality and outcomes after extracorporeal life support for pediatric In-Hospital cardiac arrest.Resuscitation · 2023Article
- Extracorporeal Cardiopulmonary Resuscitation in Infants: Outcomes and Predictors of Mortality.Journal of chest surgery · 2023Article
- Extracorporeal Membrane Oxygenation Then and Now; Broadening Indications and Availability.Critical care clinics · 2023Review
- Cognitive and Psychological Outcomes Following Pediatric Cardiac Arrest.Frontiers in pediatrics · 2022Review
- Merging Two Hospitals: The Effects on Pediatric Extracorporeal Cardiopulmonary Resuscitation Outcomes.Journal of pediatric intensive care · 2021Article
- ECPR-extracorporeal cardiopulmonary resuscitation.Indian journal of thoracic and cardiovascular surgery · 2021Article
- Neurological Monitoring and Complications of Pediatric Extracorporeal Membrane Oxygenation Support.Pediatric neurology · 2020Review
- What's new in paediatric extracorporeal life support?Intensive care medicine · 2020Article
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Authors and funding
16 authors.
Funding
Abstract
objectiveTo describe neurobehavioral outcomes and investigate factors associated with survival and survival with good neurobehavioral outcome 1 year after in-hospital cardiac arrest for children who received extracorporeal cardiopulmonary resuscitation.
designSecondary analysis of the Therapeutic Hypothermia after Pediatric Cardiac Arrest In-Hospital trial.
settingThirty-seven PICUs in the United States, Canada, and the United Kingdom. PATIENTS: Children (n = 147) resuscitated with extracorporeal cardiopulmonary resuscitation following in-hospital cardiac arrest.
interventionsNeurobehavioral status was assessed using the Vineland Adaptive Behavior Scales, Second Edition, at prearrest baseline and 12 months postarrest. Norms for Vineland Adaptive Behavior Scales, Second Edition, are 100 (mean) ± 15 (SD). Higher scores indicate better functioning. Outcomes included 12-month survival, 12-month survival with Vineland Adaptive Behavior Scales, Second Edition, decreased by less than or equal to 15 points from baseline, and 12-month survival with Vineland Adaptive Behavior Scales, Second Edition, greater than or equal to 70. MEASUREMENTS AND MAIN
resultsOf 147 children receiving extracorporeal cardiopulmonary resuscitation, 125 (85.0%) had a preexisting cardiac condition, 75 (51.0%) were postcardiac surgery, and 84 (57.1%) were less than 1 year old. Duration of chest compressions was greater than 30 minutes for 114 (77.5%). Sixty-one (41.5%) survived to 12 months, 32 (22.1%) survived to 12 months with Vineland Adaptive Behavior Scales, Second Edition, decreased by less than or equal to 15 points from baseline, and 39 (30.5%) survived to 12 months with Vineland Adaptive Behavior Scales, Second Edition, greater than or equal to 70. On multivariable analyses, open-chest cardiac massage was independently associated with greater 12-month survival with Vineland Adaptive Behavior Scales, Second Edition, decreased by less than or equal to 15 points and greater 12-month survival with Vineland Adaptive Behavior Scales, Second Edition, greater than or equal to 70. Higher minimum postarrest lactate and preexisting gastrointestinal conditions were independently associated with lower 12-month survival with Vineland Adaptive Behavior Scales, Second Edition, decreased by less than or equal to 15 points and lower 12-month survival with Vineland Adaptive Behavior Scales, Second Edition, greater than or equal to 70.
conclusionsAbout one third of children survived with good neurobehavioral outcome 1 year after receiving extracorporeal cardiopulmonary resuscitation for in-hospital arrest. Open-chest cardiac massage and minimum postarrest lactate were associated with survival with good neurobehavioral outcome at 1 year.
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