Evidence map›Paper›PMID 30422669›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Tumor-derived Autoantibodies Identify Malignant Pulmonary Nodules.

Kristin J Lastwika, Julia Kargl, Yuzheng Zhang, Xiaodong Zhu, Edward Lo, David Shelley, Jon J Ladd, Wei Wu, Paul Kinahan, Sudhakar N J Pipavath and 4 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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  18. Integrated Biomarkers for the Management of Indeterminate Pulmonary Nodules.American journal of respiratory and critical care medicine · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 5 countries.

Kristin J Lastwika1 Translational Research Program, Public Health Sciences.
Julia Kargl2 Human Biology Division.
Yuzheng Zhang5 Program in Biostatistics and Biomathematics, Division of Public Health Sciences, and.
Xiaodong Zhu2 Human Biology Division.
Edward Lo1 Translational Research Program, Public Health Sciences.
David Shelley1 Translational Research Program, Public Health Sciences.
Jon J Ladd1 Translational Research Program, Public Health Sciences.
Wei Wu6 Department of Radiology, University of Washington, Seattle, Washington; and.
Paul Kinahan6 Department of Radiology, University of Washington, Seattle, Washington; and.
Sudhakar N J Pipavath6 Department of Radiology, University of Washington, Seattle, Washington; and.
Timothy W Randolph5 Program in Biostatistics and Biomathematics, Division of Public Health Sciences, and.
Melissa Shipley3 Clinical Research Division.
Paul D Lampe1 Translational Research Program, Public Health Sciences.
A McGarry Houghton2 Human Biology Division.
Centro Regional de Derechos Humanos y Justicia de Género, Corporación Humanas · CLBiomathematics and Statistics Scotland · GBUniversity of Washington · USCenter for Clinical Research (United States) · USFred Hutch Cancer Center · USMedical University of Graz · ATTongji University · CN

Funding

Project 4: Risk stratification for pulmonary nodules detected by CT imaging using plasma and imaging biomarkersP50CA228944 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI A McGarry Houghton · 2019 to 2026
$19.6M
Hybrid Plasma Markers that Complement CT Imaging for Early Lung Cancer DetectionU01CA186157 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HOUGHTON, A MCGARRY, LAMPE, PAUL D. · 2015 to 2019
$2.5M
Proteomic, Glycomic and Autoantibody Lung Cancer Biomarker ValidationU01CA185097 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HOUGHTON, A MCGARRY, LAMPE, PAUL D. · 2014 to 2016
$1.1M
Hybrid Glycoproteomic and Autoantibody Biomarkers for Lung Cancer Early DetectionF32CA200265 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LASTWIKA, KRISTIN J · 2016 to 2019
$183k
NCI NIH HHS F32 CA200265NCI NIH HHS P50 CA228944NCI NIH HHS U01 CA185097NCI NIH HHS U01 CA186157
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAutoantibodiesBiomarkers, TumorCarcinoma, Non-Small-Cell LungDiagnosis, DifferentialEarly Detection of CancerFemaleHumansLung NeoplasmsMaleMiddle AgedMultiple Pulmonary NodulesSensitivity and SpecificityTomography, X-Ray ComputedAutoantibodiesBiomarkers, TumorB cellscomputed tomography imagingearly detectionindeterminate pulmonary noduleslung cancer

Identifiers

PMID30422669
PMCPMC6519849
OpenAlexW2901043034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.