Evidence map›Paper›PMID 30422337›Full record

ReviewJournal of the European Academy of Dermatology and Venereology : JEADV2019

Non-invasive imaging in dermatology and the unique potential of raster-scan optoacoustic mesoscopy.

B Hindelang, J Aguirre, M Schwarz, A Berezhnoi, K Eyerich, V Ntziachristos, T Biedermann, U Darsow

Abstract readReview
In one paragraph

Review in Journal of the European Academy of Dermatology and Venereology : JEADV, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Non-invasive characterization of melanoma depth at single-cell resolution.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. [Optoacoustic imaging-Applications and advancements of innovative imaging techniques].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021
    Review
  15. Article
  16. Article
  17. [Artificial intelligence in pediatric surgery : Present and future].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020
    Review
  18. Role of pH Value in Clinically Relevant Diagnosis.Diagnostics (Basel, Switzerland) · 2020
    Review
  19. Article
  20. [Molecular diagnostics of hand eczema].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

B HindelangDepartment of Dermatology and Allergy, Technische Universität München, Munich, Germany.
J AguirreChair of Biological Imaging, Technische Universität München, Munich, Germany.
M SchwarzChair of Biological Imaging, Technische Universität München, Munich, Germany.
A BerezhnoiChair of Biological Imaging, Technische Universität München, Munich, Germany.
K EyerichDepartment of Dermatology and Allergy, Technische Universität München, Munich, Germany.
V NtziachristosChair of Biological Imaging, Technische Universität München, Munich, Germany.
T BiedermannDepartment of Dermatology and Allergy, Technische Universität München, Munich, Germany.
U DarsowDepartment of Dermatology and Allergy, Technische Universität München, Munich, Germany.

Funding

European Research Council (ERC) 694968European Union's Horizon 2020 687866
6 · The paper itself

Abstract

In recent years, several non-invasive imaging methods have been introduced to facilitate diagnostics and therapy monitoring in dermatology. The microscopic imaging methods are restricted in their penetration depth, while the mesoscopic methods probe deeper but provide only morphological, not functional, information. 'Raster-scan optoacoustic mesoscopy' (RSOM), an emerging new imaging technique, combines deep penetration with contrast based on light absorption, which provides morphological, molecular and functional information. Here, we compare the capabilities and limitations of currently available dermatological imaging methods and highlight the principles and unique abilities of RSOM. We illustrate the clinical potential of RSOM, in particular for non-invasive diagnosis and monitoring of inflammatory and oncological skin diseases.

Indexed as

DermatologyDiagnostic ImagingHumansMicroscopyPhotoacoustic TechniquesSkin

Identifiers

PMID30422337
PMCPMC6563473

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.