Evidence map›Paper›PMID 30422092›Full record

SynthesisRadiology2019

Native T1 and Extracellular Volume Measurements by Cardiac MRI in Healthy Adults: A Meta-Analysis.

Matthew Gottbrecht, Christopher M Kramer, Michael Salerno

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 8 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 8 syntheses or guidelines pooled it, 117 citations in OpenAlex.

  1. Pooled it
  2. Society for Cardiovascular Magnetic Resonance reference values ("normal values") in cardiovascular magnetic resonance: 2025 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Guideline
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
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  8. Pooled it
  9. Article
  10. Review
  11. Age-, sex-, and segment-specific myocardial T1 and T2 reference values in a healthy cohort: a prospective single-center study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  12. Article
  13. The spatial ventricular gradient is a non-invasive, vectorcardiographic correlate of cardiac fibrosis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Myocardial native T1 and extracellular volume measurements at 5T: Feasibility study and initial experience.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Matthew GottbrechtFrom the Departments of Medicine (M.G., C.M.K., M.S.), Radiology (C.M.K., M.S.), and Biomedical Engineering (M.S.) and Cardiovascular Imaging Center (M.G., C.M.K., M.S.), University of Virginia Health System, 1215 Lee St, Box 800158, Charlottesville, VA 22908.ORCID 0000-0001-5245-9356
Christopher M KramerFrom the Departments of Medicine (M.G., C.M.K., M.S.), Radiology (C.M.K., M.S.), and Biomedical Engineering (M.S.) and Cardiovascular Imaging Center (M.G., C.M.K., M.S.), University of Virginia Health System, 1215 Lee St, Box 800158, Charlottesville, VA 22908.
Michael SalernoFrom the Departments of Medicine (M.G., C.M.K., M.S.), Radiology (C.M.K., M.S.), and Biomedical Engineering (M.S.) and Cardiovascular Imaging Center (M.G., C.M.K., M.S.), University of Virginia Health System, 1215 Lee St, Box 800158, Charlottesville, VA 22908.ORCID 0000-0001-7051-1031
Texas A&M University System · US

Funding

Training in Cardiovascular Imaging ResearchT32EB003841 · NIBIB · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Jonathan R Lindner · 2004 to 2026
$4.4M
High-Resolution Whole Heart Quantitative CMR Perfusion Imaging in Ischemic Heart DiseaseR01HL131919 · NHLBI · UNIVERSITY OF VIRGINIA · PI ENNIS, DANIEL B · 2017 to 2021
$3.5M
Improved MR Techniques for Coronary Artery ImagingR01HL079110 · NHLBI · UNIVERSITY OF VIRGINIA · PI MEYER, CRAIG H · 2006 to 2010
$1.8M
Quantitative Adenosine Stress CMR with Spiral Pulse SequencesK23HL112910 · NHLBI · UNIVERSITY OF VIRGINIA · PI SALERNO, MICHAEL · 2012 to 2016
$789k
NHLBI NIH HHS K23 HL112910NHLBI NIH HHS R01 HL079110NHLBI NIH HHS R01 HL131919NIBIB NIH HHS T32 EB003841
6 · The paper itself

Abstract

Purpose To summarize the literature by performing a systematic review and pooled analysis of the data, to understand the extent of variability among studies of native T1 and extracellular volume (ECV) measurements, and to identify covariates that account for heterogeneity between studies. Materials and Methods PubMed, Web of Science, and Cochrane Central were searched for native T1 and ECV measurements of the left ventricle in health adult study participants. The search terms used were "T1 mapping heart," "Native T1 heart," and "ECV heart." Summary means were generated with random-effects modeling. Heterogeneity was assessed by using the inconsistency factor (I

Indexed as

Cardiac Imaging TechniquesMagnetic Resonance ImagingFemaleHeartHeart VentriclesHumansMaleMiddle AgedReference Values

Identifiers

PMID30422092
PMCPMC6358026
OpenAlexW2901419502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.