ArticleAmerican journal on intellectual and developmental disabilities2018
Associations Between Medical History, Cognition, and Behavior in Youth With Down Syndrome: A Report From the Down Syndrome Cognition Project.
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Article in American journal on intellectual and developmental disabilities, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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19citing papers in PubMed, 2 pooled it
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What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Use of Virtual and Computational Technologies in the Psychomotor and Cognitive Development of Children with Down Syndrome: A Systematic Literature Review.International journal of environmental research and public health · 2022Pooled it
- Pooled it
- An Altered Relationship between Soluble TREM2 and Inflammatory Markers in Young Adults with Down Syndrome: A Preliminary Report.Journal of immunology (Baltimore, Md. : 1950) · 2020Trial
- Lifestyle intervention and cognitive outcomes in Down syndrome: a horizon 21 European Down syndrome consortium scoping review.Journal of neurodevelopmental disorders · 2026Article
- Baseline Neuropsychological Characteristics of Adolescents and Young Adults with Down Syndrome Who Participated in Two Clinical Trials of the Drug Memantine.Brain sciences · 2025Article
- The National Institutes of Health INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project: Accelerating research discoveries for people with Down syndrome across the lifespan.American journal of medical genetics. Part C, Seminars in medical genetics · 2024Review
- Associations Among Sex, Cognitive Ability, and Autism Symptoms in Individuals with Down Syndrome.Journal of autism and developmental disorders · 2024Article
- Using the Social Skills Improvement System (SSiS) Rating Scales to assess social skills in youth with Down syndrome.Frontiers in psychology · 2023Article
- Profiles of Caregiver-Reported Executive Function in Children with Down Syndrome.Brain sciences · 2022Article
- Associations among co-occurring medical conditions and cognition, language, and behavior in Down syndrome.Research in developmental disabilities · 2022Article
- Circadian Sleep-Activity Rhythm across Ages in Down Syndrome.Brain sciences · 2021Article
- Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome.Scientific reports · 2021Article
- Capturing cognitive and behavioral variability among individuals with Down syndrome: a latent profile analysis.Journal of neurodevelopmental disorders · 2021Article
- Opportunities, barriers, and recommendations in down syndrome research.Translational science of rare diseases · 2021Article
- The Influence of Hearing Impairment on Mental Age in Down Syndrome: Preliminary Results.Frontiers in pediatrics · 2021Article
- Gestational age is related to symptoms of attention-deficit/hyperactivity disorder in late-preterm to full-term children and adolescents with down syndrome.Scientific reports · 2020Article
- Recent advances in our understanding of neurodevelopmental outcomes in congenital heart disease.Current opinion in pediatrics · 2019Review
- Characteristics Associated with Autism Spectrum Disorder Risk in Individuals with Down Syndrome.Journal of autism and developmental disorders · 2019Article
- Comparison of Receptive Verbal Abilities Assessed Using the KBIT-2 and BPVS3 in Adults With Down Syndrome.Frontiers in psychology · 2018Article
Corrections and comments
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Authors and funding
16 authors.
Tracie C RosserTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Jamie O EdginTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
George T CaponeTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Debra R HamiltonTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Emily G AllenTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Kenneth J DooleyTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Payal AnandTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
John F StrangTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
A Chelsea ArmourTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Michelle A Frank-CrawfordTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Marie Moore ChannellTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Elizabeth I PierpontTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Eleanor FeingoldTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Cheryl L MaslenTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Roger H ReevesTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Stephanie L ShermanTracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.
Funding
WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 1985 to 2015
$25.2MWaisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI CHANG, QIANG · 2016 to 2020
$6.0MNICHD NIH HHS P30 HD003352NICHD NIH HHS U54 HD090256
Abstract
The cause of the high degree of variability in cognition and behavior among individuals with Down syndrome (DS) is unknown. We hypothesized that birth defects requiring surgery in the first years of life (congenital heart defects and gastrointestinal defects) might affect an individual's level of function. We used data from the first 234 individuals, age 6-25 years, enrolled in the Down Syndrome Cognition Project (DSCP) to test this hypothesis. Data were drawn from medical records, parent interviews, and a cognitive and behavior assessment battery. Results did not support our hypothesis. That is, we found no evidence that either birth defect was associated with poorer outcomes, adjusting for gender, race/ethnicity, and socioeconomic status. Implications for study design and measurement are discussed.
Indexed as
AdolescentAdultBehavioral SymptomsChildCognitive DysfunctionDigestive System AbnormalitiesDown SyndromeFemaleHeart Defects, CongenitalHumansMaleYoung Adultbehaviorbirth defectcognitioncongenital heart defectDown syndromegastrointestinal defectintellectual disabilityneuropsychological assessmenttrisomy 21
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