Evidence map›Paper›PMID 30421882›Full record

ArticleRevista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia2018

[Utilisation of first-line antibiotics six years after a multifaceted intervention].

J M Molero, M Gómez, G Guerra, J D Alcántara, J Ortega, G García, V Pineda, S Munuera, M Cid, M J Monedero and 6 more

Abstract read
In one paragraph

Article in Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

J M MoleroJosé María Molero, Centro de Salud San Andrés, Madrid C/ Alberto Palacios, 22, 28021 Madrid. Spain. jmolerog@gmail.com.
M Gómez
G Guerra
J D Alcántara
J Ortega
G García
V Pineda
S Munuera
M Cid
M J Monedero
J M Ribas
J M Cots
A Moragas
L Bjerrum
C Llor
Grupo de Trabajo HAPPY AUDIT 3
Instituto Palacios · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNo study has evaluated the impact of a multifaceted intervention on the quality of the antibiotics prescribed more than 5 years later.

methodsA total of 210 general practitioners (GP) from eight different regions of Spain were asked to participate in two registrations of respiratory tract infections (RTI) in 2008, before, and in 2009, just after a multifaceted intervention including prescriber feedback, clinical guidelines, training sessions focused on appropriate antibiotic prescribing, workshop on rapid tests and provision of these tests in the GP consultation. They were all again invited to participate in a similar registration in 2015. A new group of clinicians from the same areas who had never participated in antimicrobial stewardship courses were also invited to participate and acted as controls.

resultsThe 121 GPs who continued the study (57.6%) and the 117 control GPs registered 22,407 RTIs. The antibiotic most commonly prescribed was amoxicillin and clavulanic acid, prescribed in 1,801 cases (8.1% of the total), followed by amoxicillin (1,372 prescriptions, 6.2%), being lower among GPs just after the intervention. The third leading antibiotic among GPs just after the intervention was penicillin V (127 cases, 3.3%) whereas macrolides ranked third in the other three groups of GPs.

conclusionsThe use of first-line antibiotic for RTIs wanes over time after an intervention, but their utilisation is still significantly greater among intervened clinicians six years later compared to GPs who have never been exposed to any antimicrobial stewardship programmes.

Indexed as

Antimicrobial StewardshipDrug UtilizationAnti-Bacterial AgentsBacterial InfectionsDrug PrescriptionsHumansPractice Patterns, Physicians'RegistriesRespiratory Tract InfectionsSpainAnti-Bacterial Agents

Identifiers

PMID30421882
PMCPMC6254481
OpenAlexW3005986435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.