Evidence map›Paper›PMID 30421263›Full record

ArticleNanoscale research letters2018

Fluorescent Neoglycoprotein Gold Nanoclusters: Synthesis and Applications in Plant Lectin Sensing and Cell Imaging.

Katarzyna Alicja Brzezicka, Sonia Serna, Niels Christian Reichardt

Open access · goldAbstract read
In one paragraph

Article in Nanoscale research letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Katarzyna Alicja BrzezickaGlycotechnology Laboratory, CIC biomaGUNE, Paseo Miramon 182, 20014, San Sebastian, Spain. ka.brzezicka@gmail.com.ORCID http://orcid.org/0000-0002-7566-451X
Sonia SernaGlycotechnology Laboratory, CIC biomaGUNE, Paseo Miramon 182, 20014, San Sebastian, Spain.
Niels Christian ReichardtGlycotechnology Laboratory, CIC biomaGUNE, Paseo Miramon 182, 20014, San Sebastian, Spain. nreichardt@cicbiomagune.es.
CIC biomaGUNE · ESScripps Research Institute · US

Funding

Spanish Ministry of Economy and Competiveness CTQ2011-27874
6 · The paper itself

Abstract

Carbohydrate-protein interactions mediate fundamental biological processes, such as fertilization, cell signaling, or host-pathogen communication. However, because of the enormous complexity of glycan recognition events, new tools enabling their analysis or applications emerge in recent years. Here, we describe the first preparation of neoglycoprotein functionalized fluorescent gold nanoclusters, containing a biantennary N-glycan G0 as targeting molecule, ovalbumin as carrier/model antigen, and a fluorescent gold core as imaging probe (G0-OVA-AuNCs). Subsequently, we demonstrate the utility of generated G0-OVA-AuNCs for specific sensing of plant lectins and in vitro imaging of dendritic cells.

Indexed as

Carbohydrate-protein interactionsDendritic cellsGold nanoclustersLectin sensingNeoglycoproteinsTargeting

Identifiers

PMID30421263
PMCPMC6232188
OpenAlexW2901536320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.