Evidence map›Paper›PMID 30421250›Full record

ArticleMagma (New York, N.Y.)2019

Fluorine-19 MRI at 21.1 T: enhanced spin-lattice relaxation of perfluoro-15-crown-5-ether and sensitivity as demonstrated in ex vivo murine neuroinflammation.

Sonia Waiczies, Jens T Rosenberg, Andre Kuehne, Ludger Starke, Paula Ramos Delgado, Jason M Millward, Christian Prinz, Joao Dos Santos Periquito, Andreas Pohlmann, Helmar Waiczies and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Magma (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. FirstTheranostics · 2023
    Article
  5. Article
  6. Review
  7. Hardware Considerations for Preclinical Magnetic Resonance of the Kidney.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  8. Data Preparation Protocol for Low Signal-to-Noise Ratio Fluorine-19 MRI.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  9. Theranostics · 2021
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Sonia WaicziesExperimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany. sonia.waiczies@mdc-berlin.de.ORCID http://orcid.org/0000-0002-9916-9572
Jens T RosenbergThe National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, USA.
Andre KuehneMRI TOOLS GmbH, Berlin, Germany.
Ludger StarkeExperimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.
Paula Ramos DelgadoExperimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.
Jason M MillwardExperimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.
Christian PrinzExperimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.
Joao Dos Santos PeriquitoExperimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.
Andreas PohlmannExperimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.
Helmar WaicziesMRI TOOLS GmbH, Berlin, Germany.
Thoralf NiendorfExperimental Ultrahigh Field MRI, Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125, Berlin, Germany.
Max Delbrück Center · DEFlorida State University · US

Funding

National High Magnetic Field Laboratory (US) 227000-110
6 · The paper itself

Abstract

objectiveFluorine MR would benefit greatly from enhancements in signal-to-noise ratio (SNR). This study examines the sensitivity gain of MATERIALS AND

methodsWe studied perfluoro-15-crown-5-ether (PFCE) at both field strengths (B

resultsCompared to 9.4 T, an SNR gain of > 3 was observed for pure PFCE and > 2 for PFCE NPs at 21.1 T using 2D-FLASH. A dependency of DISCUSSION: Enhanced SNR and T

Indexed as

Fluorine-19 Magnetic Resonance ImagingAnimalsBrainCalibrationContrast MediaCrown EthersEncephalomyelitis, Autoimmune, ExperimentalFemaleFluorineFluorocarbonsInflammationLymph NodesMiceNanoparticlesRadio WavesReproducibility of ResultsContrast MediaCrown EthersFluorineFluorocarbonsperfluoro-15-crown-5-etherSpin LabelsExperimental autoimmune encephalomyelitisFluorine-19 magnetic resonance imagingMagnetic fieldsSignal-to-noise ratio

Identifiers

PMID30421250
PMCPMC6514110
OpenAlexW2901199214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.