Evidence map›Paper›PMID 30421072›Full record

ReviewWorld journal of urology2019

Genomic classification and risk stratification of bladder cancer.

Damiano Fantini, Joshua J Meeks

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Damiano FantiniDepartment of Urology, Feinberg School of Medicine, Chicago, IL, USA.
Joshua J MeeksDepartment of Urology, Feinberg School of Medicine, Chicago, IL, USA. joshua.meeks@northwestern.edu.
Northwestern University · USRobert H. Lurie Comprehensive Cancer Center of Northwestern University

Funding

FUNCTION(S) OF THE INSULIN RECEPTOR TYROSINE KINASEF05TW003692 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI TORNQVIST, HANS E · 1985 to 1986
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The Role of EZH2 in Non-Muscle Invasive Bladder CancerI01BX003692 · VA · JESSE BROWN VA MEDICAL CENTER · PI Joshua James Meeks · 2017 to 2026
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BLRD VA I01 BX003692Office of Research and Development BX003692
6 · The paper itself

Abstract

Bladder cancer is the fourth most common cancer in men and fifth most common overall. The use of next-generation sequencing (NGS) approaches is crucial to precisely characterize the molecular defects of tumors, and this information could be combined with other clinical data, such as tumor histology and TNM staging, with the goal of precise tumor classification. In many settings, targeted NGS is evaluated in patients with first- and second-line metastatic cancer. Yet, in the decade to come we anticipate increased application of precision oncology at all stages of bladder cancer with the aim of customizing cancer treatment. Here, we review the genomic and transcriptomic features associated with risk stratification in bladder cancer and summarize the current efforts for precision oncology in localized urothelial carcinomas.

Indexed as

GenomicsHumansNeoplasm InvasivenessRisk AssessmentUrinary Bladder NeoplasmsBiomarkerBladder cancerClassifierGenetic mutationRisk-classification

Identifiers

PMID30421072
OpenAlexW2900589755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.