Evidence map›Paper›PMID 30420973›Full record

ArticleAdvances in cell and gene therapy2018

CAR T cells targeting α

Lars Wallstabe, Andreas Mades, Silke Frenz, Hermann Einsele, Christoph Rader, Michael Hudecek

Abstract read
In one paragraph

Article in Advances in cell and gene therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. CAR-T cell immunotherapy in rhabdomyosarcoma.Journal of translational medicine · 2026
    Review
  3. Review
  4. Integrin α6 Targeted Tumor Theranostics.Phenomics (Cham, Switzerland) · 2025
    Review
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  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
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  15. Review
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  17. Review
  18. Targeting integrin pathways: mechanisms and advances in therapy.Signal transduction and targeted therapy · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Lars WallstabeMedizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
Andreas MadesMedizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
Silke FrenzMedizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
Hermann EinseleMedizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
Christoph RaderDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida, USA.
Michael HudecekMedizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
Universitätsklinikum Würzburg · DEScripps Research Institute · US

Funding

Chemically Programmed Bispecific Antibodies for Cancer TherapyR01CA181258 · NCI · SCRIPPS FLORIDA · PI RADER, CHRISTOPH · 2014 to 2018
$2.0M
NCI NIH HHS R01 CA181258
6 · The paper itself

Abstract

objectiveIntegrins are heterodimeric receptors that convey cell-to-cell and cell-to-matrix interactions. Integrin α

methodsα

resultsα

conclusionsThese data establish α CLINICAL IMPLICATIONS: α

Indexed as

cancer immunotherapychimeric antigen receptor (CAR)hLM609integrin αvβ3melanoma

Identifiers

PMID30420973
PMCPMC6226260
OpenAlexW2840539135

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.