ReviewFrontiers in bioengineering and biotechnology2018
Heavy Metal Removal by Bioaccumulation Using Genetically Engineered Microorganisms.
Review in Frontiers in bioengineering and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 320 citations in OpenAlex.
- Identification and characterization of TrxA: a novel bacterial thioredoxin-metallothionein chimera.Applied microbiology and biotechnology · 2026Article
- Inhalation of cadmium oxide nanoparticles alters intestinal and pulmonary microbiomes in mice.Applied microbiology and biotechnology · 2026Article
- To Biotic or Abiotic: Biohybrid Systems for Artificial Photosynthesis.Chemical reviews · 2026Review
- Oxalate-mediated detoxification and bioaccumulation of lead and cadmium inMicrobiology (Reading, England) · 2026Article
- Emerging strategies for heavy metal removal in soils: plant-microbe interactions and omics perspectives.Archives of microbiology · 2026Review
- Draft genome sequence ofMicrobiology resource announcements · 2025Article
- Resistance to heavy metals and chromium reduction by bacteria isolated from air.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Enhanced nickel bioremediation by mutant strains of Kluyvera cryocrescens M7: a promising approach for environmental remediation.World journal of microbiology & biotechnology · 2025Article
- Optimization of copper bioremoval from hypersaline environments by the halophilic archaeon Halalkalicoccus sp. Dap5 via response surface methodology.Scientific reports · 2025Article
- Application of Yeasts as Pollutant Adsorbents.Current microbiology · 2025Review
- Exploring cadmium bioaccumulation and bioremediation mechanisms and related genes in soil microorganisms: a review.Environmental science and pollution research international · 2025Review
- From cultivation challenges of Acidobacteriota to biotechnological promises - unveiling what is needed to fully harness their potential.World journal of microbiology & biotechnology · 2025Review
- Taxonomic description ofMicrobiology spectrum · 2025Article
- Agro-industrial wastes and their application perspectives in metal decontamination using biocomposites and bacterial biomass: a review.World journal of microbiology & biotechnology · 2024Review
- Review on the impact of heavy metals from industrial wastewater effluent and removal technologies.Heliyon · 2024Review
- Revolutionizing dairy waste: emerging solutions in conjunction with microbial engineering.Biodegradation · 2024Review
- Tannery effluent treatments with mangrove fungi, grass root biomass, and biochar.World journal of microbiology & biotechnology · 2024Article
- Roles of pH and phosphate in rare earth element biosorption with living acidophilic microalgae.Applied microbiology and biotechnology · 2024Article
- Analysis of the Influence ofMolecules (Basel, Switzerland) · 2024Article
- Scalable and Consolidated Microbial Platform for Rare Earth Element Leaching and Recovery from Waste Sources.Environmental science & technology · 2024Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wastewater effluents from mines and metal refineries are often contaminated with heavy metal ions, so they pose hazards to human and environmental health. Conventional technologies to remove heavy metal ions are well-established, but the most popular methods have drawbacks: chemical precipitation generates sludge waste, and activated carbon and ion exchange resins are made from unsustainable non-renewable resources. Using microbial biomass as the platform for heavy metal ion removal is an alternative method. Specifically, bioaccumulation is a natural biological phenomenon where microorganisms use proteins to uptake and sequester metal ions in the intracellular space to utilize in cellular processes (e.g., enzyme catalysis, signaling, stabilizing charges on biomolecules). Recombinant expression of these import-storage systems in genetically engineered microorganisms allows for enhanced uptake and sequestration of heavy metal ions. This has been studied for over two decades for bioremediative applications, but successful translation to industrial-scale processes is virtually non-existent. Meanwhile, demands for metal resources are increasing while discovery rates to supply primary grade ores are not. This review re-thinks how bioaccumulation can be used and proposes that it can be developed for bioextractive applications-the removal
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.