Evidence map›Paper›PMID 30420860›Full record

ArticleFrontiers in immunology2018

Divergent lncRNA

Hunter R Gibbons, Guzel Shaginurova, Laura C Kim, Nathaniel Chapman, Charles F Spurlock, Thomas M Aune

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 1 synthesis or guideline pooled it, 122 citations in OpenAlex.

  1. Pooled it
  2. Mechanisms and therapeutic strategies of asthma: from bench to bedside.Signal transduction and targeted therapy · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Rewiring cancer epigenome: lncRNA as modulator of chromatin architecture and neoplastic transformation.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Genome biology of long non-coding RNAs in humans: A virtual karyotype.Computational and structural biotechnology journal · 2025
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hunter R GibbonsDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN, United States.
Guzel ShaginurovaDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Laura C KimProgram in Cancer Biology, Vanderbilt University, Nashville, TN, United States.
Nathaniel ChapmanDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN, United States.
Charles F SpurlockDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Thomas M AuneDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN, United States.
Vanderbilt University · USVanderbilt University Medical Center · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
MULTIDISCIPLINARY TRAINING IN MOLECULAR ENDOCRINOLOGYT32DK007563 · NIDDK · VANDERBILT UNIVERSITY · PI Richard M O'Brien · 1988 to 2026
$15.9M
IFN GAMMA GENE REGULATION IN T CELLS AND NK CELLSR01AI044924 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI AUNE, THOMAS M. · 2000 to 2019
$5.8M
LncRNAs tether transcription factors to enable locus-specific regulation and sustain memory T cell phenotypeR21AI128281 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI AUNE, THOMAS M. · 2017 to 2018
$435k
NCATS NIH HHS UL1 TR000445NIAID NIH HHS R01 AI044924NIAID NIH HHS R21 AI128281NIDDK NIH HHS T32 DK007563
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) possess a diverse array of regulatory functions including activation and silencing of gene transcription, regulation of splicing, and coordinating epigenetic modifications.

Indexed as

Cell DifferentiationCell LineChromatinCytokinesEpigenesis, GeneticGATA3 Transcription FactorGene Expression Regulation, NeoplasticHumansRNA, Long NoncodingTh2 CellsTranscription, GeneticChromatinCytokinesGATA3 protein, humanGATA3 Transcription FactorRNA, Long NoncodingepigeneticsGATA3GATA3-AS1lncRNAlong non-coding RNAR-LoopT Celltranscription

Identifiers

PMID30420860
PMCPMC6215836
OpenAlexW2899110512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.