Evidence map›Paper›PMID 30420776›Full record

ArticleNature chemistry2019

A biomimetic receptor for glucose.

Robert A Tromans, Tom S Carter, Laurent Chabanne, Matthew P Crump, Hongyu Li, Johnathan V Matlock, Michael G Orchard, Anthony P Davis

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 261 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. [Advances in injectable and transdermal glucose-responsive insulin delivery systems].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Review
  5. Article
  6. Carbohydrate-Binding Mechanism and Therapeutic Potential of Lectin Mimics.Advances in experimental medicine and biology · 2026
    Review
  7. Article
  8. Review
  9. A Synthetic Lectin for Glucuronate.ACS central science · 2025
    Article
  10. Review
  11. Molecular Tweezers for Biomimetic Recognition of Carbohydrates.Chembiochem : a European journal of chemical biology · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Precise AIE-Based Ternary Co-Assembly for Saccharide Recognition and Classification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  18. Article
  19. Discovery of selective monosaccharide receptorsOrganic & biomolecular chemistry · 2024
    Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Robert A TromansSchool of Chemistry, University of Bristol, Bristol, UK.
Tom S CarterZiylo Ltd., Unit DX, St Philips Central, Bristol, UK.ORCID http://orcid.org/0000-0001-6488-1028
Laurent ChabanneZiylo Ltd., Unit DX, St Philips Central, Bristol, UK.
Matthew P CrumpSchool of Chemistry, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-7868-5818
Hongyu LiSchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol, UK.ORCID http://orcid.org/0000-0001-5405-9401
Johnathan V MatlockZiylo Ltd., Unit DX, St Philips Central, Bristol, UK.
Michael G OrchardZiylo Ltd., Unit DX, St Philips Central, Bristol, UK.ORCID http://orcid.org/0000-0002-0651-2571
Anthony P DavisSchool of Chemistry, University of Bristol, Bristol, UK. Anthony.Davis@bristol.ac.uk.ORCID http://orcid.org/0000-0001-5213-624X
Philips (United Kingdom) · GBUniversity of Bristol · GBUniversity of the West of England · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific molecular recognition is routine for biology, but has proved difficult to achieve in synthetic systems. Carbohydrate substrates are especially challenging, because of their diversity and similarity to water, the biological solvent. Here we report a synthetic receptor for glucose, which is biomimetic in both design and capabilities. The core structure is simple and symmetrical, yet provides a cavity which almost perfectly complements the all-equatorial β-pyranoside substrate. The receptor's affinity for glucose, at K

Indexed as

Biomimetic MaterialsGlucoseReceptors, ArtificialReceptors, Cell SurfaceAnimalsHumansLectinsModels, MolecularSynthetic BiologyGlucoseglucose receptorLectinsReceptors, ArtificialReceptors, Cell Surface

Identifiers

PMID30420776
OpenAlexW2898866616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.