ArticleScientific reports2018
Correlation between genomic index lesions and mpMRI and
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Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 9% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Insights into pet-based radiogenomics in oncology: an updated systematic review.European journal of nuclear medicine and molecular imaging · 2025Pooled it
- [Prostate cancer-multiparametric MRI and alternative approaches in intervention and therapy planning].Urologie (Heidelberg, Germany) · 2023Pooled it
- Radiomics in prostate cancer imaging for a personalized treatment approach - current aspects of methodology and a systematic review on validated studies.Theranostics · 2021Pooled it
- Safety and patient-reported outcomes of multimodal PSMA PET/MRI-guided prostate biopsy: results from the prospective multicenter DEPROMP trial.World journal of urology · 2026Trial
- Recent advances and current landscape of software tools for image analysis and dosimetry in nuclear medicine.EJNMMI physics · 2026Review
- Redefining Prostate Cancer Precision: Radiogenomics, Theragnostics, and AI-Driven Biomarkers.Cancers · 2025Review
- Deep Learning of radiology-genomics integration for computational oncology: A mini review.Computational and structural biotechnology journal · 2024Review
- Review
- Article
- Review
- Role of Artificial Intelligence in Radiogenomics for Cancers in the Era of Precision Medicine.Cancers · 2022Review
- Overview of radiomics in prostate imaging and future directions.The British journal of radiology · 2022Review
- [Machine learning and multiparametric MRI for early diagnosis of prostate cancer].Der Urologe. Ausg. A · 2021Review
- Radiomics and Prostate MRI: Current Role and Future Applications.Journal of imaging · 2021Review
- Machine learning-based analysis of [European journal of nuclear medicine and molecular imaging · 2021Article
- Magnetic Resonance Imaging Based Radiomic Models of Prostate Cancer: A Narrative Review.Cancers · 2021Review
- Article
- Background, applications and challenges of radiogenomics in genitourinary tumor.American journal of cancer research · 2021Review
- Conspicuity of prostate cancer on multiparametric magnetic resonance imaging: A cross-disciplinary translational hypothesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- Genetic Landscape of Prostate Cancer Conspicuity on Multiparametric Magnetic Resonance Imaging: A Systematic Review and Bioinformatic Analysis.European urology open science · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
37 authors at 7 institutions in 3 countries.
Claudia KeschDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Jan-Philipp RadtkeDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Axel WintscheInterdisciplinary Center for Bioinformatics, University of Leipzig, Härtelstrasse 16-18, D-04107, Leipzig, Germany.
Manuel WiesenfarthDivision of Biostatistics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.
Mariska LuttjeImaging Division, University Medical Center Utrecht, Heidelberglaan 100, 3584, CX Utrecht, The Netherlands.
Claudia GaschDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Svenja DieffenbacherDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Carine PecqueuxDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Dogu TeberDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Gencay HatibogluDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Joanne Nyarangi-DixDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Tobias SimpfendörferDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Gita SchönbergDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Antonia Dimitrakopoulou-StraussClinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-0338-9472
Martin FreitagDepartment of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.
Anette DuensingCancer Therapeutics Program and Department of Pathology, Hillman Cancer Center, University of Pittsburgh School of Medicine, 5117 Centre Avenue, Pittsburgh, PA, 15213, USA.ORCID http://orcid.org/0000-0002-0168-4067
Carsten GrüllichDepartment of Medical Oncology, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, Im Neuenheimer Feld 460, D-69120, Heidelberg, Germany.
Dirk JägerDepartment of Medical Oncology, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, Im Neuenheimer Feld 460, D-69120, Heidelberg, Germany.
Michael GötzDivision of Medical Image Computing, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-0984-224X
Niels GrabeHamamatsu Tissue Imaging and Analysis Center (TIGA), BIOQUANT, University of Heidelberg, Im Neuenheimer Feld 267, D-69120, Heidelberg, Germany.
Michal-Ruth SchweigerFunctional Epigenomics, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Strasse 21, D-50931, Cologne, Germany.
Sascha PahernikDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Sven PernerPathology of the University Hospital Schleswig-Holstein, Campus Lübeck and the Research Center Borstel, Leibniz Lung Center, Ratzeburger Allee 160, D-23538 Lübeck and Parkallee 1-40, D-23845, Borstel, Germany.
Esther HerpelInstitute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, D-69120, Heidelberg, Germany.
Wilfried RothInstitute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, D-69120, Heidelberg, Germany.
Kathrin WieczorekInstitute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, D-69120, Heidelberg, Germany.
Klaus Maier-HeinDivision of Medical Image Computing, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-6626-2463
Jürgen DebusDepartment of Radiation Oncology, University Hospital Heidelberg, Im Neuenheimer Feld 400, D-69120, Heidelberg, Germany.
Uwe HaberkornClinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.
Frederik GieselClinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.
Jörg GalleInterdisciplinary Center for Bioinformatics, University of Leipzig, Härtelstrasse 16-18, D-04107, Leipzig, Germany.
Boris HadaschikDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
Heinz-Peter SchlemmerDepartment of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.
Markus HohenfellnerDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany.
David BonekampDepartment of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.
Holger SültmannCancer Genome Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Im Neuenheimer Feld 460, D-69120, Heidelberg, Germany. h.sueltmann@dkfz-heidelberg.de.
Stefan DuensingDepartment of Urology, University Hospital Heidelberg, Im Neuenheimer Feld 517, D-69120, Heidelberg, Germany. stefan.duensing@med.uni-heidelberg.de.
Heidelberg University · DEGerman Cancer Research Center · DELeipzig University · DEJohannes Gutenberg University Mainz · DEUniversity Hospital Schleswig-Holstein · DEUniversity of Cologne · DEUPMC Hillman Cancer Center · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnetic resonance imaging (MRI) and prostate specific membrane antigen (PSMA)- positron emission tomography (PET)/computed tomography (CT)-imaging of prostate cancer (PCa) are emerging techniques to assess the presence of significant disease and tumor progression. It is not known, however, whether and to what extent lesions detected by these imaging techniques correlate with genomic features of PCa. The aim of this study was therefore to define a genomic index lesion based on chromosomal copy number alterations (CNAs) as marker for tumor aggressiveness in prostate biopsies in direct correlation to multiparametric (mp) MRI and
Indexed as
AgedHumansMagnetic Resonance ImagingMalePositron Emission Tomography Computed TomographyProstateProstatic Neoplasms
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