ArticleScientific reports2018
Comparison of linear frequency and amplitude modulation for intraneural sensory feedback in bidirectional hand prostheses.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Artificial referred sensation in upper and lower limb prosthesis users: a systematic review.Journal of neural engineering · 2022Pooled it
- Characterization of multi-channel intraneural stimulation in transradial amputees.Scientific reports · 2019Trial
- Development of an electrical current stimulator for controlling biohybrid machines.Scientific reports · 2025Article
- Tactile edges and motion via patterned microstimulation of the human somatosensory cortex.Science (New York, N.Y.) · 2025Article
- Clinical Applications and Future Translation of Somatosensory Neuroprostheses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Sensory integration for neuroprostheses: from functional benefits to neural correlates.Medical & biological engineering & computing · 2024Review
- The role of stimulus periodicity on spinal cord stimulation-induced artificial sensations in rodents.Journal of neural engineering · 2024Article
- Biomimetic computer-to-brain communication enhancing naturalistic touch sensations via peripheral nerve stimulation.Nature communications · 2024Article
- Biohybrid Robotic Hand to Investigate Tactile Encoding and Sensorimotor Integration.Biomimetics (Basel, Switzerland) · 2024Article
- Neuromorphic hardware for somatosensory neuroprostheses.Nature communications · 2024Review
- Real-time adaptive cancellation of TENS feedback artifact on sEMG for prosthesis closed-loop control.Frontiers in bioengineering and biotechnology · 2024Article
- Restoration of sensory information via bionic hands.Nature biomedical engineering · 2023Review
- Wearable High Voltage Compliant Current Stimulator for Restoring Sensory Feedback.Micromachines · 2023Article
- Symbiotic electroneural and musculoskeletal framework to encode proprioception via neurostimulation: ProprioStim.iScience · 2023Article
- Non-rectangular neurostimulation waveforms elicit varied sensation quality and perceptive fields on the hand.Scientific reports · 2023Article
- Peripheral neurostimulation for encoding artificial somatosensations.The European journal of neuroscience · 2022Review
- Combined spatial and frequency encoding for electrotactile feedback of myoelectric signals.Experimental brain research · 2022Article
- Brain network modulation in transradial amputee with finger perception restored through biomimetic intraneural stimulation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Sensory feedback for limb prostheses in amputees.Nature materials · 2021Review
- Mechanisms of neuro-robotic prosthesis operation in leg amputees.Science advances · 2021Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies have shown that direct nerve stimulation can be used to provide sensory feedback to hand amputees. The intensity of the elicited sensations can be modulated using the amplitude or frequency of the injected stimuli. However, a comprehensive comparison of the effects of these two encoding strategies on the amputees' ability to control a prosthesis has not been performed. In this paper, we assessed the performance of two trans-radial amputees controlling a myoelectric hand prosthesis while receiving grip force sensory feedback encoded using either linear modulation of amplitude (LAM) or linear modulation of frequency (LFM) of direct nerve stimulation (namely, bidirectional prostheses). Both subjects achieved similar and significantly above-chance performance when they were asked to exploit LAM or LFM in different tasks. The feedbacks allowed them to discriminate, during manipulation through the robotic hand, objects of different compliances and shapes or different placements on the prosthesis. Similar high performances were obtained when they were asked to apply different levels of force in a random order on a dynamometer using LAM or LFM. In contrast, only the LAM strategy allowed the subjects to continuously modulate the grip pressure on the dynamometer. Furthermore, when long-lasting trains of stimulation were delivered, LFM strategy generated a very fast adaptation phenomenon in the subjects, which caused them to stop perceiving the restored sensations. Both encoding approaches were perceived as very different from the touch feelings of the healthy limb (natural). These results suggest that the choice of specific sensory feedback encodings can have an effect on user performance while grasping. In addition, our results invite the development of new approaches to provide more natural sensory feelings to the users, which could be addressed by a more biomimetic strategy in the future.
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