Evidence map›Paper›PMID 30420676›Full record

ArticleNature communications2018

Near-infrared STED nanoscopy with an engineered bacterial phytochrome.

Maria Kamper, Haisen Ta, Nickels A Jensen, Stefan W Hell, Stefan Jakobs

Abstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Bright monomeric fluorescent protein elite-niRFP704 for two-channel near-infrared STED nanoscopy.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. The near-infrared bacteriophytochrome-derived fluorescent protein PENELOPE enables RESOLFT superresolution microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Fluorescent Probes for STED Optical Nanoscopy.Nanomaterials (Basel, Switzerland) · 2021
    Review
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria KamperDepartment of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Haisen TaDepartment of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Nickels A JensenDepartment of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Stefan W HellDepartment of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Stefan JakobsDepartment of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany. sjakobs@gwdg.de.ORCID http://orcid.org/0000-0002-8028-3121

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The near infrared (NIR) optical window between the cutoff for hemoglobin absorption at 650 nm and the onset of increased water absorption at 900 nm is an attractive, yet largely unexplored, spectral regime for diffraction-unlimited super-resolution fluorescence microscopy (nanoscopy). We developed the NIR fluorescent protein SNIFP, a bright and photostable bacteriophytochrome, and demonstrate its use as a fusion tag in live-cell microscopy and STED nanoscopy. We further demonstrate dual color red-confocal/NIR-STED imaging by co-expressing SNIFP with a conventional red fluorescent protein.

Indexed as

NanotechnologyProtein EngineeringBacterial ProteinsCell SurvivalHeLa CellsHumansInfrared RaysLuminescent ProteinsMicroscopy, FluorescencePhytochromeRecombinant Fusion ProteinsBacterial ProteinsLuminescent ProteinsPhytochromeRecombinant Fusion Proteins

Identifiers

PMID30420676
PMCPMC6232180

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.