ArticleBritish journal of cancer2018
Smoking cessation sharply reduced lung cancer mortality in a historical cohort of 3185 Chinese silicotic workers from 1981 to 2014.
Article in British journal of cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Quantifying the evidence and burden of smoking behaviour on tuberculosis incidence among adult population: a systematic review and meta-analysis.Journal of global health · 2026Pooled it
- Impact of Lifestyle Modifications on Cancer Mortality: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2025Pooled it
- A comprehensive examination of the impact of environmental pollution on lung cancer: A review.Journal of advanced research · 2026Review
- Cancer Mortality in an Ageing Population: Evidence of Sex-Specific Divergence from a National Study in Poland.Cancers · 2026Article
- Leveraging geospatial data to support an implementation science approach to address lung cancer burden.JNCI cancer spectrum · 2025Article
- Risk prediction models for lung cancer in people who have never smoked: a protocol of a systematic review.Diagnostic and prognostic research · 2024Article
- Association of smoking cessation with airflow obstruction in workers with silicosis: A cohort study.PloS one · 2024Article
- Association of spirometric restriction with mortality in the silicotics: a cohort study.BMC pulmonary medicine · 2023Article
- Effect of Time Since Smoking Cessation on Lung Cancer Incidence: An Occupational Cohort With 27 Follow-Up Years.Frontiers in oncology · 2022Article
- Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults.Scientific reports · 2021Article
- Association of Silica Dust Exposure and Cigarette Smoking With Mortality Among Mine and Pottery Workers in China.JAMA network open · 2020Article
- Unfavorable Mortality-To-Incidence Ratio of Lung Cancer Is Associated with Health Care Disparity.International journal of environmental research and public health · 2018Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPopulation-based studies showed an over 50% decrease in lung cancer risk after quitting smoking for 5-6 years, but the beneficial effect in silicotics remains unknown. We aimed to rectify this knowledge gap using a large historical cohort of 3185 Chinese silicotics since 1981 and followed-up till 2014.
methodsBaseline information on workers' socio-demographics, smoking habits, occupational history, and medical history was collected. Smoking status was reassessed during follow-up. Multiple Cox proportional hazards model was performed to evaluate the impact of smoking cessation on lung cancer mortality.
resultsOverall, 1942 deaths occurred and 188 lung cancer deaths were identified. Compared with never quitters, silicotics who were new quitters had almost halved their lung cancer risk [hazard ratio (HR) = 0.51, 95%CI: 0.34-0.76], while persistent quitters had a 53% risk reduction (HR = 0.47, 95%CI: 0.33-0.66). Lung cancer mortality approximately halved after quitting smoking for 10 years. While the risk kept decreasing with years since cessation, it did not reverse back to that of never smokers. Persistent quitters with small opacities tended to have higher beneficial effects than those with large opacities.
conclusionsSmoking cessation for 10 years halved lung cancer mortality among silicotics, while the beneficial effect was prominent for patients with small opacities.
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