Evidence map›Paper›PMID 30420521›Full record

ArticleEMBO reports2019

Shelterin and subtelomeric DNA sequences control nucleosome maintenance and genome stability.

Thomas S van Emden, Marta Forn, Ignasi Forné, Zsuzsa Sarkadi, Matías Capella, Lucía Martín Caballero, Sabine Fischer-Burkart, Cornelia Brönner, Marco Simonetta, David Toczyski and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in EMBO reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 38 citations in OpenAlex.

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  14. Review
  15. Spreading and epigenetic inheritance of heterochromatin require a critical density of histone H3 lysine 9 tri-methylation.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  16. The Genomics of Plant Satellite DNA.Progress in molecular and subcellular biology · 2021
    Review
  17. Review
  18. Article
  19. Subtelomeric Transcription and its Regulation.Journal of molecular biology · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Thomas S van EmdenDepartment of Physiological Chemistry, BioMedical Center (BMC), Ludwig Maximilians University of Munich, Martinsried, Germany.
Marta FornDepartment of Physiological Chemistry, BioMedical Center (BMC), Ludwig Maximilians University of Munich, Martinsried, Germany.ORCID 0000-0002-0230-0141
Ignasi FornéProtein Analysis Unit (ZfP), BioMedical Center (BMC), Ludwig Maximilians University of Munich, Martinsried, Germany.
Zsuzsa SarkadiDepartment of Physiological Chemistry, BioMedical Center (BMC), Ludwig Maximilians University of Munich, Martinsried, Germany.
Matías CapellaDepartment of Physiological Chemistry, BioMedical Center (BMC), Ludwig Maximilians University of Munich, Martinsried, Germany.
Lucía Martín CaballeroDepartment of Physiological Chemistry, BioMedical Center (BMC), Ludwig Maximilians University of Munich, Martinsried, Germany.
Sabine Fischer-BurkartDepartment of Physiological Chemistry, BioMedical Center (BMC), Ludwig Maximilians University of Munich, Martinsried, Germany.
Cornelia BrönnerDepartment of Biochemistry, Gene Center, Ludwig Maximilians University of Munich, Munich, Germany.
Marco SimonettaDepartment of Biophysics and Biochemistry, University of California San Francisco (UCSF), San Francisco, CA, USA.
David ToczyskiDepartment of Biophysics and Biochemistry, University of California San Francisco (UCSF), San Francisco, CA, USA.
Mario HalicDepartment of Biochemistry, Gene Center, Ludwig Maximilians University of Munich, Munich, Germany.
Axel ImhofProtein Analysis Unit (ZfP), BioMedical Center (BMC), Ludwig Maximilians University of Munich, Martinsried, Germany.ORCID 0000-0003-2993-8249
Sigurd BraunDepartment of Physiological Chemistry, BioMedical Center (BMC), Ludwig Maximilians University of Munich, Martinsried, Germany sigurd.braun@bmc.med.lmu.de.ORCID 0000-0001-6399-8574
Ludwig-Maximilians-Universität München · DEMax Planck Institute of Biochemistry · DEUniversity of California, San Francisco · US

Funding

Regulation by post-translation modifications in response to stressR35GM118104 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TOCZYSKI, DAVID PAUL · 2016 to 2025
$7.2M
NIGMS NIH HHS R35 GM118104
6 · The paper itself

Abstract

Telomeres and the shelterin complex cap and protect the ends of chromosomes. Telomeres are flanked by the subtelomeric sequences that have also been implicated in telomere regulation, although their role is not well defined. Here, we show that, in

Indexed as

Genome, FungalGenomic InstabilityHeterochromatinHumansMethylationNucleosomesSchizosaccharomycesSchizosaccharomyces pombe ProteinsTelomereCcq1 protein, S pombeHeterochromatinNucleosomesSchizosaccharomyces pombe Proteinsgenome stabilityheterochromatinnucleosomesshelterintelomeres

Identifiers

PMID30420521
PMCPMC6322387
OpenAlexW2952724736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.