Evidence map›Paper›PMID 30420468›Full record

ArticleG3 (Bethesda, Md.)2019

CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in

Vinci Au, Erica Li-Leger, Greta Raymant, Stephane Flibotte, George Chen, Kiana Martin, Lisa Fernando, Claudia Doell, Federico I Rosell, Su Wang and 4 more

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
  2. Supplementation via DAF-16 andbioRxiv : the preprint server for biology · 2026
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  9. TAG-IN, a swappable strategy for endogenous gene tagging inbioRxiv : the preprint server for biology · 2026
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Vinci AuDepartment of Zoology and Michael Smith Laboratories.ORCID 0000-0002-3587-6200
Erica Li-LegerDepartment of Zoology and Michael Smith Laboratories.
Greta RaymantDepartment of Zoology and Michael Smith Laboratories.
Stephane FlibotteDepartment of Zoology and Michael Smith Laboratories.
George ChenDepartment of Zoology and Michael Smith Laboratories.
Kiana MartinDepartment of Zoology and Michael Smith Laboratories.
Lisa FernandoDepartment of Zoology and Michael Smith Laboratories.
Claudia DoellDepartment of Zoology and Michael Smith Laboratories.
Federico I RosellDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada, V6T 1Z4.
Su WangDepartment of Zoology and Michael Smith Laboratories.
Mark L EdgleyDepartment of Zoology and Michael Smith Laboratories.
Ann E RougvieDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455.
Harald HutterDepartment of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada, V5A 1S6.
Donald G MoermanDepartment of Zoology and Michael Smith Laboratories moerman@zoology.ubc.ca.
Simon Fraser University · CAUniversity of British Columbia · CAUniversity of Minnesota · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Enhancing the C. elegans animal resource through genome editingR24OD023041 · OD · UNIVERSITY OF MINNESOTA · PI ROUGVIE, ANN E., STERNBERG, PAUL WARREN · 2017 to 2024
$5.1M
CIHR MOP 93719CIHR PJT-148549NIH HHS P40 OD010440NIH HHS R24 OD023041
6 · The paper itself

Abstract

The

Indexed as

Gene EditingAnimalsCaenorhabditis elegansCRISPR-Cas SystemsGene DeletionGene Knockout TechniquesGene TargetingHomologous RecombinationMutagenesisC. elegansCRISPR/Cas9homology dependent repairmutagenesis

Identifiers

PMID30420468
PMCPMC6325907
OpenAlexW2901672380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.