Evidence map›Paper›PMID 30420454›Full record

ArticleJournal of bacteriology2019

Grace M Kroner, Michael B Wolfe, Lydia Freddolino

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 92 citations in OpenAlex.

  1. Loss of CsrA inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. The Algorithm for Reversible Jump Inference of Motifs.bioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Identification of theMicrobiology (Reading, England) · 2025
    Article
  6. Article
  7. Article
  8. Genome-wide Screening of the Escherichia coli Keio Knockout Collection Identifies Genetic Determinants of Epetraborole Hypersusceptibility.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  9. The role ofApplied and environmental microbiology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Grace M Kroner *Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Michael B Wolfe *Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Lydia FreddolinoDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, USA petefred@umich.edu.ORCID 0000-0002-5821-4226
University of Michigan · US

Funding

Cellular Biotechnology Training Program (CBTP)T32GM008353 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHWENDEMAN, ANNA · 1991 to 2021
$9.3M
Building a unified framework for understanding bacterial gene regulation and chromosomal architectureR35GM128637 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lydia Petra Freddolino · 2018 to 2026
$3.6M
Cellular Biotechnology Training Program (CBTP) - Years 31-35T32GM145304 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Guizhi Zhu · 2022 to 2026
$2.6M
Genome-wide measurement of bacterial transcriptional regulatory statesR00GM097033 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FREDDOLINO, LYDIA PETRA · 2015 to 2017
$746k
NIGMS NIH HHS R00 GM097033NIGMS NIH HHS R35 GM128637NIGMS NIH HHS T32 GM008353NIGMS NIH HHS T32 GM145304
6 · The paper itself

Abstract

The global regulator Lrp plays a crucial role in regulating metabolism, virulence, and motility in response to environmental conditions. Lrp has previously been shown to activate or repress approximately 10% of the genes in

Indexed as

Gene Expression Regulation, BacterialRegulonChromatin ImmunoprecipitationEscherichia coliEscherichia coli ProteinsGene Expression ProfilingLeucine-Responsive Regulatory ProteinSequence Analysis, DNASequence Analysis, RNAEscherichia coli ProteinsLeucine-Responsive Regulatory ProteinLrp protein, E coliChIP-seqLrptranscriptional regulationtranscription factor

Identifiers

PMID30420454
PMCPMC6349092
OpenAlexW2950018499

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.