Evidence map›Paper›PMID 30420420›Full record

ReviewJournal of the American Society of Nephrology : JASN2018

Anticoagulant-Related Nephropathy.

Sergey Brodsky, John Eikelboom, Lee A Hebert

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Review
  13. Anticoagulation in Patients with Chronic Kidney Disease.American journal of nephrology · 2024
    Review
  14. The wonders of anticoagulation.Frontiers in cardiovascular medicine · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Sergey BrodskyRenal and Transplant Pathology Laboratory, Department of Pathology and.
John EikelboomDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Lee A HebertDivision of Nephrology, Department of Internal Medicine, Ohio State University Wexner Medical Center, Columbus, Ohio; and lee.hebert@osumc.edu.
McMaster University · CAMetabolism and Renal Physiology · FRThe Ohio State University Wexner Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anticoagulant-related nephropathy (ARN) is a newly recognized form of AKI in which overanticoagulation causes profuse glomerular hemorrhage, which manifests on renal biopsy as numerous renal tubules filled with red cells and red cell casts. The glomeruli show changes, but they are not sufficient to account for the glomerular hemorrhage. We were the first to study ARN, and since then, our work has been confirmed by numerous other investigators. Oral anticoagulants have been in widespread use since the 1950s; today, >2 million patients with atrial fibrillation take an oral anticoagulant. Despite this history of widespread and prolonged exposure to oral anticoagulants, ARN was discovered only recently, suggesting that the condition may be a rare occurrence. This review chronicles the discovery of ARN, its confirmation by others, and our animal model of ARN. We also provide new data on analysis of "renal events" described in the

Indexed as

Acute Kidney InjuryAdministration, OralAnimalsAnticoagulantsCreatinineDisease Models, AnimalHumansInternational Normalized RatioKidneyPractice Guidelines as TopicRenal Insufficiency, ChronicRisk FactorsWarfarinAnticoagulantsCreatinineWarfarinchronic kidney diseasenephropathyrenal biopsy

Identifiers

PMID30420420
PMCPMC6287865
OpenAlexW2900936068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.