Evidence map›Paper›PMID 30419912›Full record

ArticleHead & face medicine2018

Extracorporeal shockwave treatment impedes tooth movement in rats.

Phimon Atsawasuwan, Yinghua Chen, Karan Ganjawalla, Albert L Kelling, Carla A Evans

Open access · goldAbstract read
In one paragraph

Article in Head & face medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Phimon AtsawasuwanDepartment of Orthodontics, University of Illinois at Chicago, College of Dentistry, 801 S. Paulina St, Chicago, Illinois, 60612, USA. patsawas@uic.edu.ORCID http://orcid.org/0000-0002-2576-060X
Yinghua ChenDepartment of Orthodontics, University of Illinois at Chicago, College of Dentistry, 801 S. Paulina St, Chicago, Illinois, 60612, USA.
Karan GanjawallaHarvard School of Dental Medicine, Boston, Massachusetts, USA.
Albert L Kelling, Raleigh, USA.
Carla A EvansDepartment of Orthodontic and Dentofacial Orthopedics, Boston University, Boston, Massachusetts, USA.
Boston University · USHarvard University · USIllinois College · USRaleigh Neurology Associates · USUniversity of Illinois Chicago · US

Funding

The Role of microRNA-21, 27 and 29 in Tooth MovementK08DE024531 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ATSAWASUWAN, PHIMON · 2015 to 2019
$697k
American Association of Orthodontists Foundation biomedical research awardNational Institute of Dental and Craniofacial Research DE024531NIDCR NIH HHS K08 DE024531University of Illinois at Chicago Wach fund
6 · The paper itself

Abstract

backgroundAccelerated tooth movement has been a topic of interest for orthodontic research recently. Surgically facilitated orthodontic treatment has been shown to be an effective approach to accelerate tooth movement; however, it remains invasive, requires additional surgery, and may increase post-operative complications. In this study, we evaluate the effects of extracorporeal shockwave treatment (ESWT), a non-invasive approach to regenerate alveolar bone, on orthodontic tooth movement in rats. MATERIALS AND

methodsSeventy-two male rats, aged 10 weeks old, were subjected to 10-cN closed-coil nickel-titanium springs for unilateral maxillary first molar tooth movement. One group of rats received a single treatment of extracorporeal shockwave treatment at 500 impulses at energy flux density 0.1 mJ/mm

resultsThe results demonstrated that tooth movement in the ESWT-treated rats (0.11 ± 0.07 mm) was impeded compared to the tooth movement in the non-ESWT-treated rats (0.44 ± 0.09 mm). ESWT up-regulated several osteoblastic and osteoclastic gene markers and cytokines; however, the effects on osteoclasts were only transient. Double-fluorescence bone labeling demonstrated that osteoblastic activity increased after ESWT treatment. There was no difference in systemic RANKL/OPG ratio between groups.

conclusionsESWT at 500 impulse at energy flux density 0.1 mJ/mm

Indexed as

Bone RemodelingExtracorporeal Shockwave TherapyTooth Movement TechniquesAnimalsMaleMolarRatsRats, Sprague-DawleyESWTOrthodonticRatShockwaveTooth movement

Identifiers

PMID30419912
PMCPMC6233511
OpenAlexW2901322035

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.