ReviewBiomedical engineering online2018
Biomedical engineer's guide to the clinical aspects of intensive care mechanical ventilation.
Review in Biomedical engineering online, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Prospects and Limitations of Bioprinting in Studying Human Cells' Responses to Extreme Environments.Bioengineering (Basel, Switzerland) · 2026Article
- Respiratory pressure and flow data collection device providing a framework for closed-loop mechanical ventilation.HardwareX · 2025Article
- Effects of Extrusion Pressure During 3D Printing on Viability of Human Bronchial Epithelial Cells in 3D Printed Samples.Biomimetics (Basel, Switzerland) · 2025Article
- Evaluation of flow control using PID versus fuzzy logic in an electropneumatic circuit for pulmonary ventilation applications.PloS one · 2025Article
- CARETestLung: A mechanical test lung with Configurable airway Resistance, lung Elastance, and breathing efforts.HardwareX · 2024Article
- Automated evaluation of typical patient-ventilator asynchronies based on lung hysteretic responses.Biomedical engineering online · 2023Article
- Non-invasive over-distension measurements: data driven vs model-based.Journal of clinical monitoring and computing · 2023Article
- Reconstructing asynchrony for mechanical ventilation using a hysteresis loop virtual patient model.Biomedical engineering online · 2022Article
- Stochastic integrated model-based protocol for volume-controlled ventilation setting.Biomedical engineering online · 2022Article
- Model-based patient matching for in-parallel pressure-controlled ventilation.Biomedical engineering online · 2022Article
- Whole-lung finite-element models for mechanical ventilation and respiratory research applications.Frontiers in physiology · 2022Article
- Stochastic Modelling of Respiratory System Elastance for Mechanically Ventilated Respiratory Failure Patients.Annals of biomedical engineering · 2021Observational
- Model-based Patient Matching for in-parallel Multiplexing Mechanical Ventilation Support.IFAC-PapersOnLine · 2021Article
- Risk-Based Care: Let's Think Outside the Box.Frontiers in medicine · 2021Article
- GlasVent-The Rapidly Deployable Emergency Ventilator.Global challenges (Hoboken, NJ) · 2020Article
- A Nonlinear Hysteretic Model for Automated Prediction of Lung Mechanics during Mechanical Ventilation.IFAC-PapersOnLine · 2020Article
- Optimising mechanical ventilation through model-based methods and automation.Annual reviews in control · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundMechanical ventilation is an essential therapy to support critically ill respiratory failure patients. Current standards of care consist of generalised approaches, such as the use of positive end expiratory pressure to inspired oxygen fraction (PEEP-FiO DISCUSSION: This review presents the significant clinical aspects and variables of ventilation management, the potential risks associated with suboptimal ventilation management, and a review of the major recent attempts to improve ventilation in the context of these variables. The unique aspect of this review is a focus on these key elements relevant to engineering new approaches. In particular, the need for ventilation strategies which consider, and directly account for, the significant differences in patient condition, disease etiology, and progression within patients is demonstrated with the subsequent requirement for optimal ventilation strategies to titrate for patient- and time-specific conditions.
conclusionEngineered, protective lung strategies that can directly account for and manage inter- and intra-patient variability thus offer great potential to improve both individual care, as well as cohort clinical outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.