Evidence map›Paper›PMID 30419841›Full record

ArticleBMC infectious diseases2018

Persistent candidemia in very low birth weight neonates: risk factors and clinical significance.

Jinjian Fu, Yanling Ding, Yongjiang Jiang, Shengfu Mo, Shaolin Xu, Peixu Qin

Abstract read
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jinjian FuDepartment of Laboratory, Liuzhou Maternity and Child Healthcare Hospital, 50th Yingshan Road, Chengzhong District, Liuzhou, 545001, China. fujinjianaa@126.com.
Yanling DingDepartment of Laboratory, Liuzhou Maternity and Child Healthcare Hospital, 50th Yingshan Road, Chengzhong District, Liuzhou, 545001, China.
Yongjiang JiangDepartment of Neonatology, Liuzhou Maternity and Child Health Care Hospital, Liuzhou, 545001, China.
Shengfu MoDepartment of Laboratory, Liuzhou Maternity and Child Healthcare Hospital, 50th Yingshan Road, Chengzhong District, Liuzhou, 545001, China.
Shaolin XuDepartment of Laboratory, Liuzhou Maternity and Child Healthcare Hospital, 50th Yingshan Road, Chengzhong District, Liuzhou, 545001, China.
Peixu QinDepartment of Laboratory, Liuzhou Maternity and Child Healthcare Hospital, 50th Yingshan Road, Chengzhong District, Liuzhou, 545001, China.

Funding

Guangxi Medical and Health Self-funding Project No Z20170509 and No Z20180022Natural Science Foundation of Guangxi Province 2015GXNSFBA139129the Liuzhou Science and Technology Bureau Project No2017BD20201
6 · The paper itself

Abstract

backgroundThe prevalence and risk factors for persistent candidemia among very low birth weight infants are poorly understood. This study aimed to investigate the epidemiology of persistent candidemia over a 4-year period in a neonatal intensive care unit (NICU) in Liuzhou, China.

methodsWe retrospectively extracted demographic data, risk factors, microbiological results and outcomes of very low birth weight infants with candidemia in our hospital between January 2012 and November 2015. Persistent candidemia was defined as a positive blood culture for > 5 days. Logistic regression was used to identify risk factors associated with persistent candidemia.

resultsOf 48 neonates with candidemia, 28 had persistent candidemia. Both mechanical ventilation and intubation were significantly associated with increased rates of persistent candidemia (P = 0.044 and 0.004, respectively). The case fatality rate for the persistent candidemia group was 14.3%.

conclusionThe rate of persistent candidemia was high among very low birth weight neonates. Mechanical ventilation and intubation were the major factors associated with the development of persistent candidemia. This study highlights the importance of intensive prevention and effective treatment among neonates with persistent candidemia.

Indexed as

Infant, Very Low Birth WeightCandidemiaChinaCross InfectionFemaleHospitalsHumansInfantInfant, NewbornInfant, Newborn, DiseasesIntensive Care Units, NeonatalIntubationMalePrevalenceRespiration, ArtificialRetrospective StudiesEpidemiologyNeonatesPersistent candidemiaVery low birth weight

Identifiers

PMID30419841
PMCPMC6233606

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.