ArticleBMC infectious diseases2018
Surgical outcomes of infectious spondylitis after vertebroplasty, and comparisons between pyogenic and tuberculosis.
Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Incidence and Independent Risk Factors of Spinal Infection After Vertebral Augmentation: A Multicenter Propensity-Matched Case-Control Study.Neurospine · 2026Article
- Vertebral infection after kyphoplasty: distinguishing misdiagnosis from true postoperative infection and implications for management.Journal of orthopaedic surgery and research · 2026Article
- Case Report: Diagnostic and therapeutic challenges of secondary spinal tuberculosis following percutaneous vertebroplasty: a case of staged surgery with bone cement retention report.Frontiers in surgery · 2026Article
- Posterior debridement and corpectomy via removal of the spinal canal's lateral wall approach for infection after vertebral augmentation: a technique note and early outcome.Asian spine journal · 2025Article
- Linoleic acid addition preventsBiofilm · 2025Article
- Prophylactic Antibiotics in Vertebroplasty and Kyphoplasty: A Nationwide Analysis of Infection Rates and Antibiotic Use in South Korea.Antibiotics (Basel, Switzerland) · 2025Article
- Deep Learning for Discrimination of Early Spinal Tuberculosis from Acute Osteoporotic Vertebral Fracture on CT.Infection and drug resistance · 2025Article
- Article
- Spinal infection after vertebral augmentation: a covert complication with serious havoc.Archives of orthopaedic and trauma surgery · 2024Article
- Tuberculous Spondylitis and Paravertebral Abscess Formation Following Vertebroplasty: A Case Report and Review of the Literature.Infection and drug resistance · 2024Article
- A rare case of aggressive pyogenic spondylitis with giant abscesses after vertebral augmentation.Joint diseases and related surgery · 2023Article
- Multidisciplinary Care of a Vertebral Fracture in a Patient with Hematopoietic Stem Cell Transplant: Safety Appropriateness in Interventional Pain Management and Rehabilitation Considerations.Healthcare (Basel, Switzerland) · 2022Article
- Risk factors for tuberculous or nontuberculous spondylitis after percutaneous vertebroplasty or kyphoplasty in patients with osteoporotic vertebral compression fracture: A case-control study.Frontiers in surgery · 2022Article
- Simultaneous-onset infectious spondylitis with vertebral fracture mimicking an acute osteoporotic vertebral fracture erroneously treated with balloon kyphoplasty: illustrative case.Journal of neurosurgery. Case lessons · 2021Article
- Debridement and corpectomy via single posterior approach to treat pyogenic spondylitis after vertebral augmentation.BMC musculoskeletal disorders · 2021Article
- An unusual Staphylococcus saccharolyticus spondylodiscitis post kyphoplasty: a case report.BMC infectious diseases · 2020Article
- Vertebral collapse and polymethylmethacrylate breakage after vertebroplasty: A case report.Medicine · 2019Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfection after vertebroplasty (VP) is a rare but serious complication. Previous literatures showed most pathogens for infection after VP were bacteria; tuberculosis (TB) induced infection after VP was extremely rare. We reported our treatment experiences of cases with infectious spondylitis after VP, and compared the differences between developed pyogenic and TB spondylitis.
methodsFrom January 2001 to December 2015, 5749 patients had undergone VP at our department were reviewed retrospectively. The causative organisms were obtained from tissue culture of revision surgery. Parameters including type of surgery, the interval between VP and revision surgery, neurologic status, and visual analog scale (VAS) of back pain were recorded. Laboratory data at the time of VP and revision surgery were collected. Charlson comorbidity index (CCI), preoperative bacteremia, urinary tract infection (UTI), pulmonary TB history were also analyzed.
resultsEighteen patients were confirmed with developed infectious spondylitis after VP (0.32%, 18/5749). Two were male and 16 were female. The median age at VP was 73.4 years. Nine patients were TB and the other nine patients were pyogenic. The interval between VP and revision surgery ranged from 7 to 1140 days (mean 123.2 days). The most common type of revision surgery was anterior combined with posterior surgery. Seven patients developed neurologic deficit before revision surgery. Three patients died within 6 months after revision surgery, with a mortality of 16.7%. Finally, VAS of back pain was improved from 7.4 to 3.1. Seven patients could walk normally, the other 8 patients had some degree of disability. Both pyogenic and TB group had similar age, sex, and CCI distribution. The interval between VP and revision surgery was shorter in the patients with pyogenic organisms (75.9 vs 170.6 days). At revision surgery, WBC and CRP were prominently elevated in the pyogenic group. Five in the pyogenic group had UTI and bacteremia; five in TB group had a history of lung TB.
conclusionsInfection spondylitis after VP required major surgery for salvage with a relevant part of residual disability. Before VP, any bacteremia/UTI or history of pulmonary TB should be reviewed rigorously; any elevation of infection parameters should be scrutinized strictly.
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