Evidence map›Paper›PMID 30419799›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2019

The Association of Maternal Age With Fetal Growth and Newborn Measures: The Mumbai Maternal Nutrition Project (MMNP).

Chiara Di Gravio, Ashwin Lawande, Ramesh D Potdar, Sirazul A Sahariah, Meera Gandhi, Nick Brown, Harsha Chopra, Harshad Sane, Sarah H Kehoe, Ella Marley-Zagar and 3 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  5. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Chiara Di GravioMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom. cdg@mrc.soton.ac.uk.
Ashwin LawandeDr Joshi Imaging Clinic, Mumbai, India.
Ramesh D PotdarCentre for the Study of Social Change, Mumbai, India.
Sirazul A SahariahCentre for the Study of Social Change, Mumbai, India.
Meera GandhiCentre for the Study of Social Change, Mumbai, India.
Nick BrownInternational Centre for Maternal and Child Health, Akademia Sjukhuset, University of Uppsala MTC-huset, Uppsala, Sweden.
Harsha ChopraCentre for the Study of Social Change, Mumbai, India.
Harshad SaneCentre for the Study of Social Change, Mumbai, India.
Sarah H KehoeMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom.
Ella Marley-ZagarMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom.
Barrie M MargettsPublic Health Nutrition, University of Southampton, Southampton, United Kingdom.
Alan A JacksonNIHR Southampton Biomedical Research Centre, Southampton, United Kingdom.
Caroline H D FallMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom.
Social Change and Development · INMRC Lifecourse Epidemiology Unit · GBUniversity of Southampton · GBJoshi Hospital · INNIHR Southampton Biomedical Research Centre · GBSouthampton General Hospital · GBUppsala University Hospital · SE

Funding

Medical Research Council G0400519Medical Research Council MC_U147574247Medical Research Council MC_UP_A620_1016Medical Research Council MC_UU_12011/3Wellcome TrustWellcome Trust WT074048
6 · The paper itself

Abstract

backgroundYoung maternal age is associated with poorer birth outcomes, but the mechanisms are incompletely understood. Using data from a prospective cohort of pregnant women living in Mumbai slums, India, we tested whether lower maternal age was associated with adverse fetal growth.

methodsFetal crown-rump length (CRL) was recorded at a median (interquartile range, IQR) of 10 weeks' gestation (9-10 weeks). Head circumference (HC), biparietal diameter (BPD), femur length (FL), and abdominal circumference (AC) were recorded at 19 (19-20) and 29 (28-30) weeks. Newborns were measured at a median (IQR) of 2 days (1-3 days) from delivery. Gestation was assessed using prospectively collected menstrual period dates.

resultsThe sample comprised 1653 singleton fetuses without major congenital abnormalities, of whom 1360 had newborn measurements. Fetuses of younger mothers had smaller CRL (0.01 standard deviation [SD] per year of maternal age; 95% confidence interval CI: 0.00-0.02

conclusionFetuses of younger mothers were smaller from the first trimester onward and grew slower, independently of known confounding factors.

Indexed as

Child DevelopmentFetal DevelopmentMaternal AgeMaternal Nutritional Physiological PhenomenaNutritional StatusAbdomenAdolescentAdultBirth WeightCrown-Rump LengthFemaleFemurFetal Growth RetardationGestational AgeHeadHumansfetal biometryIndiamaternal agenewbornpregnancyultrasound

Identifiers

PMID30419799
PMCPMC6637817
OpenAlexW2901153803

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.