Evidence map›Paper›PMID 30419730›Full record

ArticleThe Korean journal of parasitology2018

Comparative Assessment of Diagnostic Performances of Two Commercial Rapid Diagnostic Test Kits for Detection of Plasmodium spp. in Ugandan Patients with Malaria.

Young Yil Bahk, Seo Hye Park, Woojoo Lee, Kyoung Jin, Seong Kyu Ahn, Byoung-Kuk Na, Tong-Soo Kim

Open access · diamondAbstract readComparative Study
In one paragraph

Article in The Korean journal of parasitology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Rapid diagnostic tests for Plasmodium vivax malaria in endemic countries.The Cochrane database of systematic reviews · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Young Yil BahkDepartment of Biotechnology, College of Biomedical and Health Science, Konkuk University, Chungju 27478, Korea.
Seo Hye ParkDepartment of Tropical Medicine, Inha University College of Medicine, Incheon 22212, Korea.
Woojoo LeeDepartment of Statistics, Inha University College of Natural Sciences, Incheon 22212, Korea.
Kyoung JinKorea Health Evaluation Institute, Sahmyook University, Seoul 01795, Korea.
Seong Kyu AhnDepartment of Tropical Medicine, Inha University College of Medicine, Incheon 22212, Korea.
Byoung-Kuk NaKorea Health Evaluation Institute, Sahmyook University, Seoul 01795, Korea.
Tong-Soo KimDepartment of Statistics, Inha University College of Natural Sciences, Incheon 22212, Korea.
Inha University · KRSahmyook University · KRKonkuk University · KR

Funding

Inha University
6 · The paper itself

Abstract

Prompt diagnosis of malaria cases with rapid diagnostic tests (RDTs) has been widely adopted as an effective malaria diagnostic tool in many malaria endemic countries, primarily due to their easy operation, fast result output, and straightforward interpretation. However, there has been controversy about the diagnostic accuracy of RDTs. This study was conducted to evaluate the diagnostic performances of the 2 commercially available malaria RDT kits, RapiGEN Malaria Ag Pf/Pv (pLDH/pLDH) and Asan EasyTestTM Malaria Ag Pf/Pv (HRP-2/pLDH) for their abilities to detect Plasmodium species in blood samples collected from Ugandan patients with malaria. To evaluate the diagnostic performances of these 2 RDT kits, 229 blood samples were tested for malaria infection by microscopic examination and a species-specific nested polymerase chain reaction. The detection sensitivities for P. falciparum of Malaria Ag Pf/Pv (pLDH/pLDH) and Asan EasyTestTM Malaria Ag Pf/Pv (HRP-2/pLDH) were 87.83% and 89.57%, respectively. The specificities of the 2 RDTs were 100% for P. falciparum and mixed P. falciparum/P. vivax infections. These results suggest that the 2 RDT kits showed reasonable levels of diagnostic performances for detection of the malaria parasites from Ugandan patients. However, neither kit could effectively detect P. falciparum infections with low parasitaemia (<500 parasites/μl).

Indexed as

Reagent Kits, DiagnosticHumansMalariaPlasmodiumSensitivity and SpecificityUgandaReagent Kits, Diagnosticdiagnostic performanceMalariarapid diagnostic testUganda

Identifiers

PMID30419730
PMCPMC6243188
OpenAlexW2899155327

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.