Evidence map›Paper›PMID 30419414›Full record

ArticleClinical imaging

Relationship between current smoking, visual CT findings and emphysema index in cigarette smokers.

Sung Shick Jou, Kunihiro Yagihashi, Jordan Alexander Zach, David Lynch, Young Ju Suh, COPDGene Investigators

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Clinical imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Article
  5. Reconsidering the Utility of Race-Specific Lung Function Prediction Equations.American journal of respiratory and critical care medicine · 2022
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Sung Shick JouDepartment of Radiology, Soonchunhyang University Cheonan Hospital, 31 Soonchunhyang 6-gil, Dongnamgu, Cheonan-si, Chungchengnam-do 311511, Republic of Korea. Electronic address: ssmri@schmc.ac.kr.
Kunihiro YagihashiDepartment of Radiology, St. Marianna University School of Medicine, 2-16-1, Sugao, Miyamae-ku, Kawasaki 216-8511, Japan.
Jordan Alexander ZachDivision of Radiology, National Jewish Health, Denver, CO, United States of America.
David LynchDivision of Radiology, National Jewish Health, Denver, CO, United States of America.
Young Ju SuhDepartment of Biomedical Sciences College of Medicine, Inha University Incheon, Republic of Korea.
COPDGene Investigators
National Jewish Health · USInha University · KRSoonchunhyang University · KRSt. Marianna University School of Medicine · JP

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Metabolomic signatures of empysema and COPD progression in the COPDGene cohortR01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2012 to 2016
$31.1M
(2 of 2) Genetic Epidemiology of COPDR01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2012 to 2016
$18.9M
NHLBI NIH HHS R01 HL089856NHLBI NIH HHS R01 HL089897NHLBI NIH HHS U01 HL089897
6 · The paper itself

Abstract

purposeTo evaluate whether visual CT findings could account for the effect of current smoking.

methods500 CT scans were visually evaluated within each lobe. A multivariate model for emphysema index was constructed containing previously described confounders in addition to the visual components associated with smoking status.

resultsCurrent smokers displayed 23% less visual emphysema, 19% more airway wall thickening, and 188% more centrilogular nodule than former smokers (all p < 0.001). The effect of current smoking on the emphysema index decreased after adjustment with confounders and visual parameters.

conclusionsVisual CT findings could partially account for the effect of current smoking.

Indexed as

SmokersAgedFemaleHumansLungMaleMiddle AgedPulmonary EmphysemaSmokingTomography, X-Ray ComputedChronic obstructive pulmonary diseaseEmphysemaQuantitative computed tomographySmoking

Identifiers

PMID30419414
PMCPMC6633913
OpenAlexW2899088083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.