Evidence map›Paper›PMID 30419157›Full record

ArticleRisk analysis : an official publication of the Society for Risk Analysis2019

Information Hazards in Biotechnology.

Gregory Lewis, Piers Millett, Anders Sandberg, Andrew Snyder-Beattie, Gigi Gronvall

Abstract read
In one paragraph

Article in Risk analysis : an official publication of the Society for Risk Analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Functional and antigenic constraints on the Nipah virus fusion protein.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Review
  4. Functional and antigenic constraints on the Nipah virus fusion protein.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Five Things Not to Do When Discovering a Biosecurity Vulnerability.Applied biosafety : journal of the American Biological Safety Association · 2024
    Article
  10. Practical Questions for Securing Nucleic Acid Synthesis.Applied biosafety : journal of the American Biological Safety Association · 2024
    Article
  11. Developing a Common Global Baseline for Nucleic Acid Synthesis Screening.Applied biosafety : journal of the American Biological Safety Association · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Principles of synthetic biology.Essays in biochemistry · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gregory LewisFuture of Humanity Institute, Oxford University, Oxford, UK.
Piers MillettFuture of Humanity Institute, Oxford University, Oxford, UK.
Anders SandbergFuture of Humanity Institute, Oxford University, Oxford, UK.
Andrew Snyder-BeattieFuture of Humanity Institute, Oxford University, Oxford, UK.
Gigi GronvallCentre for Health Security, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Funding

European Research Council No. 669751Open Philanthropy Project
6 · The paper itself

Abstract

With the advance of biotechnology, biological information, rather than biological materials, is increasingly the object of principal security concern. We argue that both in theory and in practice, existing security approaches in biology are poorly suited to manage hazardous biological information, and use the cases of Mousepox, H5N1 gain of function, and Botulinum toxin H to highlight these ongoing challenges. We suggest that mitigation of these hazards can be improved if one can: (1) anticipate hazard potential before scientific work is performed; (2) consider how much the new information would likely help both good and bad actors; and (3) aim to disclose information in the manner that maximally disadvantages bad actors versus good ones.

Indexed as

Computer SecuritySafetyAnimalsBiotechnologyBioterrorismBotulinum ToxinsDecision MakingEctromelia, InfectiousHazardous SubstancesHumansInfluenza A Virus, H5N1 SubtypeInfluenza, HumanRiskSecurity MeasuresBotulinum ToxinsHazardous SubstancesBiotechnologydual-use research of concerninformation hazards

Identifiers

PMID30419157
PMCPMC6519142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.