Evidence map›Paper›PMID 30419025›Full record

ArticlePLoS neglected tropical diseases2018

The prevalence of lymphatic filariasis infection and disease following six rounds of mass drug administration in Mandalay Region, Myanmar.

Benjamin F R Dickson, Patricia M Graves, Ni Ni Aye, Thet Wai Nwe, Tint Wai, San San Win, Myint Shwe, Janet Douglass, Richard S Bradbury, William J McBride

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Benjamin F R DicksonCollege of Medicine & Dentistry, Division of Tropical Health and Medicine, James Cook University, Cairns, Queensland, Australia.ORCID 0000-0003-0821-8920
Patricia M GravesCollege of Public Health, Medical and Veterinary Sciences, Division of Tropical Health and Medicine, James Cook University, Cairns, Queensland, Australia.ORCID 0000-0002-5215-3901
Ni Ni AyeVector Borne Disease Control Unit, Ministry of Health and Sport, Naypyitaw, Myanmar.
Thet Wai NweVector Borne Disease Control Unit, Ministry of Health and Sport, Naypyitaw, Myanmar.
Tint WaiRegional Vector Borne Disease Control Unit, Ministry of Health and Sport, Mandalay, Myanmar.
San San WinWorld Health Organization, Yangon, Myanmar.
Myint ShweGeneral Practitioner, Mandalay, Myanmar.
Janet DouglassCollege of Public Health, Medical and Veterinary Sciences, Division of Tropical Health and Medicine, James Cook University, Cairns, Queensland, Australia.ORCID 0000-0002-3097-3132
Richard S BradburySchool of Health, Medical and Applied Sciences, Central Queensland University, North Rockhampton, Queensland, Australia.
William J McBrideCollege of Medicine & Dentistry, Division of Tropical Health and Medicine, James Cook University, Cairns, Queensland, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphatic filariasis is widely endemic in Myanmar. Despite the establishment of an elimination program in 2000, knowledge of the remaining burden of disease relies predominantly on programmatic information. To assist the program, we conducted an independent cross-sectional household cluster survey to determine the prevalence of filariasis infection, morbidity and mass-drug administration coverage in four townships of the Mandalay Region: Amarapura, Patheingyi, Tada-U and Wundwin. The survey included 1014 individuals from 430 randomly selected households in 24 villages. Household members one year and older were assessed for antigenaemia using immunochromatographic test cards and if positive, microfilaraemia by night-time thick blood smear. Participants 15 years and older were assessed for filariasis morbidity by ultrasound-assisted clinical examination. The overall prevalence of infection was 2.63% by antigenaemia (95% confidence interval (CI) 1.71-4.04%) and 1.03% by microfilaraemia (95%CI 0.59-1.47%). The prevalence of hydrocoele in adult males was 2.78% (95%CI 1.23-6.15%) and of lymphoedema in both genders was 0% (95%CI 0-0.45%). These results indicate the persistence of filarial infection and transmission despite six rounds of annual mass drug administration and highlight the need for further rounds as well as the implementation of morbidity management programs in the country.

Indexed as

AdolescentAdultAgedAged, 80 and overAlbendazoleAnimalsChildChild, PreschoolCross-Sectional StudiesDiethylcarbamazineElephantiasis, FilarialFemaleFilaricidesHumansInfantLymphedemaAlbendazoleDiethylcarbamazineFilaricides

Identifiers

PMID30419025
PMCPMC6258426

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.