Evidence map›Paper›PMID 30418685›Full record

ArticleProtein science : a publication of the Protein Society2019

Parsing redox potentials of five ferredoxins found within Thermotoga maritima.

Stephanie J Maiocco, Arthur J Arcinas, Squire J Booker, Sean J Elliott

Open access · bronzeAbstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
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  7. Understanding the role of electron donors in the reaction catalyzed by Tsrm, a cobalamin-dependent radical S-adenosylmethionine methylase.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Stephanie J MaioccoDepartment of Chemistry, Boston University, Boston, Massachusetts, 02215.
Arthur J ArcinasDepartment of Biochemistry and Molecular, The Pennsylvania State University, University Park, Pennsylvania, 16802.
Squire J BookerDepartment of Biochemistry and Molecular, The Pennsylvania State University, University Park, Pennsylvania, 16802.
Sean J ElliottDepartment of Chemistry, Boston University, Boston, Massachusetts, 02215.
Pennsylvania State University · USBoston University · USUniversity of Massachusetts Boston · US

Funding

Radical Mechanisms of Iron-Sulfur ProteinsR35GM122595 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI SQUIRE J. BOOKER · 2017 to 2026
$3.4M
Redox Reactions of the AdoMet Radical Enzyme SuperfamilyR01GM120283 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI ELLIOTT, SEAN J · 2016 to 2019
$1.3M
Mechanisms of Radical-Dependent Biological MethylationR01GM101957 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI BOOKER, SQUIRE J. · 2012 to 2015
$1.0M
Howard Hughes Medical InstituteNIGMS NIH HHS GM-101957NIGMS NIH HHS GM-120283NIGMS NIH HHS GM-122595NIGMS NIH HHS R01 GM101957NIGMS NIH HHS R01 GM120283NIGMS NIH HHS R35 GM122595
6 · The paper itself

Abstract

Most organisms contain multiple soluble protein-based redox carriers such as members of the ferredoxin (Fd) family, that contain one or more iron-sulfur clusters. The potential redundancy of Fd proteins is poorly understood, particularly in connection to the ability of Fd proteins to deliver reducing equivalents to members of the "radical SAM," or S-adenosylmethionine radical enzyme (ARE) superfamily, where the activity of all known AREs requires that an essential iron-sulfur cluster bound by the enzyme be reduced to the catalytically relevant [Fe

Indexed as

FerredoxinsOxidation-ReductionThermotoga maritimaFerredoxinsferredoxiniron-sulfur clusterredox homeostasisredox potentialS-adenosylmethioninethiomethylation

Identifiers

PMID30418685
PMCPMC6295886
OpenAlexW2901310721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.