Evidence map›Paper›PMID 30418427›Full record

ArticleTransplantation2019

Ethnic and Age Disparities in Outcomes Among Liver Transplant Waitlist Candidates.

Margaux N Mustian, Brittany A Shelton, Paul A MacLennan, Rhiannon D Reed, Jared A White, Devin E Eckhoff, Jayme E Locke, Richard M Allman, Stephen H Gray

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Longer travel and traffic are associated with adult liver transplant waitlist mortality in the United States.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  4. Article
  5. Article
  6. Impact of Payer Status on Delisting Among Liver Transplant Candidates in the United States.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2021
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Margaux N MustianDivision of Transplantation. Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Brittany A SheltonDivision of Transplantation. Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Paul A MacLennanDivision of Transplantation. Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Rhiannon D ReedDivision of Transplantation. Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Jared A WhiteDivision of Transplantation. Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Devin E EckhoffDivision of Transplantation. Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Jayme E LockeDivision of Transplantation. Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Richard M AllmanDepartment of Medicine, George Washington University School of Medicine, Washington, DC.
Stephen H GrayDivision of Transplantation. Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
George Washington University · US

Funding

Research Education CoreP30AG031054 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DURANT, RAEGAN WINSTON · 2007 to 2025
$11.6M
TRAINING IN CELLULAR PHYSIOLOGY MEMBRANE TRANSPORTT32DK007545 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUTIERREZ, ORLANDO M · 1987 to 2023
$4.5M
NIA NIH HHS P30 AG031054NIDDK NIH HHS T32 DK007545
6 · The paper itself

Abstract

backgroundDespite the increasing prevalence of end-stage liver disease in older adults, there is no consensus to determine suitability for liver transplantation (LT) in the elderly. Disparities in LT access exist, with a disproportionately lower percentage of African Americans (AAs) receiving LT. Understanding waitlist outcomes in older adults, specifically AAs, will identify opportunities to improve LT access for this vulnerable population.

methodsAll adult, liver-only white and AA LT waitlist candidates (January 1, 2003 to October 1, 2015) were identified in the Scientific Registry of Transplant Recipients. Age and race categories were defined: younger white (age <60 years), younger AA, older white (age, ≥60 years), and older AA. Outcomes were delisting, transplantation, and mortality and were modeled using Fine and Gray competing risks.

resultsAmong 101 805 candidates, 58.4% underwent transplantation, 14.7% died while listed, and 21.4% were delisted. Among those delisted, 36.1% died, whereas 7.4% were subsequently relisted. Both older AAs and older whites were more likely than younger whites to be delisted and to die after delisting. Older whites had higher incidence of waitlist mortality than younger whites (subdistribution hazard ratio, 1.07; 95% confidence interval, 1.01-1.13). All AAs and older whites had decreased incidence of LT, compared with younger whites.

conclusionsBoth older age and AA race were associated with decreased cumulative incidence of transplantation. Independent of race, older candidates had increased incidences of delisting and mortality after delisting than younger whites. Our findings support the need for interventions to ensure medical suitability for LT among older adults and to address disparities in LT access for AAs.

Indexed as

Black or African AmericanHealthcare DisparitiesHealth Services AccessibilityLiver TransplantationWaiting ListsWhite PeopleAge FactorsDatabases, FactualEnd Stage Liver DiseaseFemaleHumansIncidenceMaleMiddle AgedPrevalenceRegistries

Identifiers

PMID30418427
PMCPMC6509018
OpenAlexW2883773964

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.