ReviewAnesthesiology2019
Contribution of Baroreceptor Function to Pain Perception and Perioperative Outcomes.
Review in Anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 51 citations in OpenAlex.
- Hunyuan zhuang improves interoception: evidence from an expert-novice study and a pilot randomized controlled trial.Scientific reports · 2026Trial
- Effect of transauricular nerve stimulation on perioperative pain: a single-blind, analyser-masked, randomised controlled trial.British journal of anaesthesia · 2023Trial
- Continuous autonomic system monitoring during neurosurgical procedures -proof of concept.Journal of clinical monitoring and computing · 2026Article
- Associations of Arterial Blood Pressure With Radiographic Knee Osteoarthritis and Pain Sensitivity in Middle-Aged and Older Adults.European journal of pain (London, England) · 2026Article
- Pressure point: blood flow restriction exercise and the pain paradox in musculoskeletal injury and persistent pain populations-a narrative review.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- Soma to neuron communication links stress adaptation to stress avoidance behavior.bioRxiv : the preprint server for biology · 2025Article
- The role of the sympathetic component of the autonomic nervous system on pain before and after third molar extraction- an observational cohort study.BMC anesthesiology · 2025Observational
- Anti-nociceptive properties of cardiopulmonary baroreceptors in patients with chronic back pain.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Effects of Apnea-Induced Hypoxia on Hypoalgesia in Healthy Subjects.Sports (Basel, Switzerland) · 2024Article
- What influences post-operative opioid requirements for tibial fractures?British journal of pain · 2024Article
- Low-Intensity Focused Ultrasound to the Human Dorsal Anterior Cingulate Attenuates Acute Pain Perception and Autonomic Responses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Higher Cardiovagal Baroreflex Sensitivity Predicts Increased Pain Outcomes After Cardiothoracic Surgery.The journal of pain · 2024Article
- Baroreceptor-Inspired Microneedle Skin Patch for Pressure-Controlled Drug Release.BME frontiers · 2024Article
- Associations Between Resting Heart Rate, Resting Blood Pressure, Psychological Variables and Pain Processing in Chronic Whiplash-Associated Disorder: A Cross-Sectional Study.Pain medicine (Malden, Mass.) · 2022Article
- Intraoperative Assessment of Surgical Stress Response Using Nociception Monitor under General Anesthesia and Postoperative Complications: A Narrative Review.Journal of clinical medicine · 2022Review
- A Novel Method for Baroreflex Sensitivity Estimation Using Modulated Gaussian Filter.Sensors (Basel, Switzerland) · 2022Article
- A graph-embedded topic model enables characterization of diverse pain phenotypes among UK biobank individuals.iScience · 2022Article
- A trio of biological rhythms and their relevance in rhythmic mechanical stimulation of cell cultures.Frontiers in psychology · 2022Article
- Heart Rate Variability during Auricular Acupressure at Heart Point in Healthy Volunteers: A Pilot Study.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Dissociation between reduced pain and arterial blood pressure following epidural spinal cord stimulation in patients with chronic pain: A retrospective study.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 2 countries.
Funding
Abstract
Baroreceptors are mechanosensitive elements of the peripheral nervous system that maintain homeostasis by coordinating physiologic responses to external and internal stimuli. While it is recognized that carotid and cardiopulmonary baroreceptor reflexes modulate autonomic output to mitigate excessive fluctuations in arterial blood pressure and to maintain intravascular volume, increasing evidence suggests that baroreflex pathways also project to key regions of the central nervous system that regulate somatosensory, somatomotor, and central nervous system arousal. In addition to maintaining autonomic homeostasis, baroreceptor activity modulates the perception of pain, as well as neuroimmune, neuroendocrine, and cognitive responses to physical and psychologic stressors. This review summarizes the role that baroreceptor pathways play in modulating acute and chronic pain perception. The contribution of baroreceptor function to postoperative outcomes is also presented. Finally, methods that enhance baroreceptor function, which hold promise in improving postoperative and pain management outcomes, are presented.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.