Evidence map›Paper›PMID 30418187›Full record

ReviewCurrent opinion in endocrinology, diabetes, and obesity2019

Central control of gastrointestinal motility.

Kirsteen N Browning, R Alberto Travagli

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Current opinion in endocrinology, diabetes, and obesity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06205446 (Application of Diaphragmatic Breathing in Patients With Disorders of Gut-brain Interaction), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06205446 nacompletednot on this mapstarted 2023, after this paper: background citation

Application of Diaphragmatic Breathing in Patients With Disorders of Gut-brain Interaction: Impact on Gastrointestinal and Psychological Symptoms as Well as Autonomic Nervous System

TypeinterventionalSponsorBuddhist Tzu Chi General HospitalRan2023 to 2024Enrolled125ConditionsIrritable Bowel Syndrome, Healthy Subjects, Functional Gastrointestinal Disorders, Laryngopharyngeal RefluxArmsHealthy subjects : abdominal breathing, Laryngopharyngeal reflux disease subjects : abdominal breathing, Dyspepsia subjects : abdominal breathing, Irritable bowel disorder : abdominal breathing
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Noninvasive electrical neuromodulation for gastrointestinal motility disorders.Expert review of gastroenterology & hepatology · 2023
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kirsteen N BrowningDepartment of Neural and Behavioral Science, Penn State College of Medicine, Hershey, Pennsylvania, USA.
R Alberto Travagli
Pennsylvania State University · US

Funding

BRAINSTEM CIRCUITS CONTROLLING GASTROINTESTINAL FUNCTIONR01DK055530 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROWNING, KIRSTEEN NAIRN · 1998 to 2020
$4.6M
Vagal Dysregulation in Neonatal Gastrointestinal PathologyR01DK099350 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KOPENHAVER DOHENY, KIM, TRAVAGLI, RENATO ALBERTO · 2014 to 2017
$2.2M
Influence of diet on the development of homeostatic neurocircuitsR01DK111667 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BROWNING, KIRSTEEN NAIRN · 2018 to 2021
$1.6M
The effects of glucose on central vagal brainstem circuitsR01DK078364 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BROWNING, KIRSTEEN NAIRN · 2010 to 2014
$1.4M
NIDDK NIH HHS R01 DK055530NIDDK NIH HHS R01 DK078364NIDDK NIH HHS R01 DK099350NIDDK NIH HHS R01 DK111667
6 · The paper itself

Abstract

purpose of reviewThis review summarizes the organization and structure of vagal neurocircuits controlling the upper gastrointestinal tract, and more recent studies investigating their role in the regulation of gastric motility under physiological, as well as pathophysiological, conditions. RECENT

findingsVagal neurocircuits regulating gastric functions are highly plastic, and open to modulation by a variety of inputs, both peripheral and central. Recent research in the fields of obesity, development, stress, and neurological disorders highlight the importance of central inputs onto these brainstem neurocircuits in the regulation of gastric motility. SUMMARY: Recognition of the pivotal role that the central nervous system exerts in the regulation, integration, and modulation of gastric motility should serve to encourage research into central mechanisms regulating peripheral motility disorders.

Indexed as

AnimalsGastrointestinal MotilityGastrointestinal TractHumansNerve NetVagus Nerve

Identifiers

PMID30418187
PMCPMC6512320
OpenAlexW2900904147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.