Evidence map›Paper›PMID 30418128›Full record

ReviewBlood transfusion = Trasfusione del sangue2019

Prevention and management of acute reactions to intravenous iron in surgical patients.

Susana Gómez-Ramírez, Aryeh Shander, Donat R Spahn, Michael Auerbach, Giancarlo M Liumbruno, Stefania Vaglio, Manuel Muñoz

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Blood transfusion = Trasfusione del sangue, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05590260 (Prevention of Iron Deficiency Anemia Post-delivery), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05590260 phase3completednot on this mapstarted 2023, after this paper: background citation

Prevention of Iron Deficiency Anemia Post-delivery (PRIORITY Trial): A Randomized Controlled Trial of the Global Network for Women's and Children's Health Research

TypeinterventionalSponsorNICHD Global Network for Women's and Children's HealthRan2023 to 2025Enrolled4,857ConditionsPostpartum AnemiaArmsFerric carboxymaltose (FCM) and folic acid tablets, Oral iron tablets and folic acid tablets
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Observational
  5. Article
  6. Article
  7. Observational
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Associations of Iron Sucrose and Intradialytic Blood Pressure.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Article
  14. Article
  15. Hypersensitivity to Intravenous Iron Preparations.Children (Basel, Switzerland) · 2022
    Review
  16. Article
  17. Article
  18. Iron deficiency without anaemia: a diagnosis that matters.Clinical medicine (London, England) · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Susana Gómez-RamírezPerioperative Transfusion Medicine, Department of Surgical Specialties, Biochemistry and Immunology, School of Medicine, University of Málaga, Spain.
Aryeh ShanderDepartments of Anaesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, New Jersey, United States of America.
Donat R SpahnInstitute of Anaesthesiology, University and University Hospital of Zurich, Zurich, Switzerland.
Michael AuerbachDepartment of Medicine, School of Medicine, Georgetown University Washington, DC, United States of America.
Giancarlo M LiumbrunoItalian National Blood Centre, National Institute of Health, Rome, Italy.
Stefania VaglioItalian National Blood Centre, National Institute of Health, Rome, Italy.
Manuel MuñozPerioperative Transfusion Medicine, Department of Surgical Specialties, Biochemistry and Immunology, School of Medicine, University of Málaga, Spain.
Hospital Clínico Universitario Virgen de la Victoria · ESUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Absolute or functional iron deficiency is the most prevalent cause of anaemia in surgical patients, and its correction is a fundamental strategy within "Patient Blood Management" programmes. Offering perioperative oral iron for treating iron deficiency anaemia is still recommended, but intravenous iron has been demonstrated to be superior in most cases. However, the long-standing prejudice against intravenous iron administration, which is thought to induce anaphylaxis, hypotension and shock, still persists. With currently available intravenous iron formulations, minor infusion reactions are not common. These self-limited reactions are due to labile iron and not hypersensitivity. Aggressively treating infusion reactions with H

Indexed as

Administration, IntravenousAnaphylaxisAnemia, Iron-DeficiencyDisease ManagementHumansHypotensionIronRisk FactorsIron

Identifiers

PMID30418128
PMCPMC6476739
OpenAlexW2907541981

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.