Evidence map›Paper›PMID 30417887›Full record

ArticleJournal of visualized experiments : JoVE2018

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse.

Nodir Madrahimov, Abdurasul Khalikov, Erin C Boyle, Ruslan Natanov, Ann-Kathrin Knoefel, Thierry Siemeni, Klaus Hoeffler, Axel Haverich, Ulrich Maus, Christian Kuehn

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nodir MadrahimovDepartment of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School; Madrahimov.Nodir@mh-hannover.de.
Abdurasul KhalikovDepartment of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School.
Erin C BoyleDepartment of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School.
Ruslan NatanovDepartment of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School.
Ann-Kathrin KnoefelDepartment of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School.
Thierry SiemeniDepartment of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School.
Klaus HoefflerDepartment of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School.
Axel HaverichDepartment of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School.
Ulrich MausDepartment of Pneumology, Hannover Medical School.
Christian KuehnDepartment of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of extracorporeal membrane oxygenation (ECMO) has increased substantially in recent years. ECMO has become a reliable and effective therapy for acute as well as end-stage lung diseases. With the increase in clinical demand and prolonged use of ECMO, procedural optimization and prevention of multi-organ damage are of critical importance. The aim of this protocol is to present a detailed technique of veno-venous ECMO in a non-intubated, spontaneously breathing mouse. This protocol demonstrates the technical design of the ECMO and surgical steps. This murine ECMO model will facilitate the study of pathophysiology related to ECMO (e.g., inflammation,bleeding and thromboembolic events). Due to the abundance of genetically modified mice, the molecular mechanisms involved in ECMO-related complications can also be dissected.

Indexed as

AnimalsExtracorporeal Membrane OxygenationHumansMice

Identifiers

PMID30417887
PMCPMC6235594
OpenAlexW2898544099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.