ArticleJournal of diabetes investigation2019
Fasting triglycerides and glucose index is more suitable for the identification of metabolically unhealthy individuals in the Chinese adult population: A nationwide study.
Article in Journal of diabetes investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
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Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of triglyceride-glucose index and its related parameters with the risk of stroke: a meta-analysis.BMC neurology · 2025Pooled it
- An open label randomized controlled trial of the effects of rice bran oil on cardiometabolic risk factors, lipid peroxidation and antioxidant status in overweight/obese adults with metabolic syndrome.Lipids in health and disease · 2024Trial
- Curcumin Offers No Additional Benefit to Lifestyle Intervention on Cardiometabolic Status in Patients with Non-Alcoholic Fatty Liver Disease.Nutrients · 2022Trial
- Rice bran oil could favorably ameliorate atherogenicity and insulin resistance indices among men with coronary artery disease: post hoc analysis of a randomized controlled trial.Lipids in health and disease · 2021Trial
- The triglyceride-glucose index as a predictor of cardiovascular disease: an umbrella review of meta-analyses.Annals of medicine and surgery (2012) · 2026Article
- TyHGB as a predictive marker for preeclampsia: association with increased risk in pregnant women with normal glucose tolerance.Lipids in health and disease · 2026Article
- Obesity as a predictor of atherogenic dyslipidemia in patients with metabolic dysfunction associated steatotic liver disease.Scientific reports · 2026Article
- Analysis of mortality risk and influencing factors in female patients with young-onset type 2 diabetes.Frontiers in endocrinology · 2026Article
- The "Futile Labour" Paradox: occupational physical activity fails to offset diabetes burden and is associated with microvascular stress signals in rural older adults.Frontiers in public health · 2026Article
- Higher Dietary Insulinemic Potential, and Triglyceride-Glucose (TyG)-BMI Index may Contribute to Coronary Artery Disease Severity: a Cross-Sectional Study.Journal of epidemiology and global health · 2025Article
- Association of body mass index combined with triglyceride-glucose index in cardiovascular disease risk: a prospective cohort study.Scientific reports · 2025Article
- The relationship between the triglyceride-glucose index and functional outcomes in patients with aneurysmal subarachnoid hemorrhage: a retrospective cohort study.European journal of medical research · 2025Article
- Developmental Trends of Metabolic Syndrome in the Past Two Decades: A Narrative Review.Journal of clinical medicine · 2025Review
- Association between the triglyceride glucose index and the risk of acute respiratory failure in patients with acute pancreatitis.BMC gastroenterology · 2025Article
- Metabolic Syndrome and Insulin Resistance in Romania.International journal of molecular sciences · 2025Article
- Pre-pregnancy BMI modifies the associations between triglyceride-glucose index in early pregnancy and adverse perinatal outcomes: a 5-year cohort study of 67,936 women in China.Diabetology & metabolic syndrome · 2025Article
- 1-hour post-load plasma glucose: a reliable marker of insulin resistance in type 2 diabetes, as determined by the TyG index.Frontiers in endocrinology · 2025Article
- The relationship between triglyceride-glucose index and serum neurofilament light chain: Findings from NHANES 2013-2014.PloS one · 2025Article
- Association of triglyceride glucose index with diabetic retinopathy in middle-aged and elderly ambulatory type 2 diabetic patients.Frontiers in endocrinology · 2025Article
- Evaluating indices of insulin resistance and estimating the prevalence of insulin resistance in a large biobank cohort.Frontiers in endocrinology · 2025Article
22 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors.
Funding
Abstract
AIMS/
introductionMetabolic unhealth can be defined by the components of metabolic syndrome, which is closely connected to insulin resistance. We aimed to determine a simple index to identify metabolic unhealth in the Chinese adult population. MATERIALS AND
methodsA total of 30,291 individuals were screened from the China National Diabetes and Metabolic Disorders Study carried out from June 2007 to May 2008. Metabolic unhealth was defined using components of metabolic syndrome, except waist circumference. We compared the three surrogate indices of insulin resistance: the product of fasting triglycerides and glucose (TyG), triglycerides divided by high-density lipoprotein cholesterol and the metabolic score for insulin resistance for the evaluation of metabolic status.
resultsAll indices had high sensitivity and specificity for the identification of metabolic unhealth, especially the TyG index with an area under the curve of 0.863 for men and 0.867 for women. Participants were divided into subgroups for further analysis. The TyG index also showed high diagnostic values, especially for younger individuals and men with normal waist circumference. Sex-specific cut-offs for three indices were also used to define metabolic unhealth. The TyG index showed the highest agreement with κ values of 0.603 and 0.605 for men and women between the components of metabolic syndrome and three indices.
conclusionsWe propose that the TyG index, just read in one blood laboratory test report, is simpler and more suitable for the identification of metabolically unhealthy individuals as well as who have high risk of cardiometabolic diseases of the Chinese adult population.
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