ArticleAngewandte Chemie (International ed. in English)2019
Controlled and Tunable Loading and Release of Vesicles by Using Gigahertz Acoustics.
Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Biomimetic nanovesicles and nanotechnology for oral and maxillofacial diseases.Discover nano · 2026Review
- Thermally Driven Dynamic Behaviors in Polymeric Vesicles.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Isolation Techniques of Micro/Nano-Scaled Species for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- High-Efficiency Drug Loading in Lipid Vesicles by MEMS-Driven Gigahertz Acoustic Streaming.Micromachines · 2025Article
- Exploiting Sound for Emerging Applications of Extracellular Vesicles.Nano research · 2024Article
- Direct isolation of small extracellular vesicles from human blood using viscoelastic microfluidics.Science advances · 2023Article
- Manufacturing polymeric porous capsules.Chemical communications (Cambridge, England) · 2022Review
- Vesicle-based artificial cells: materials, construction methods and applications.Materials horizons · 2022Review
- Sonoporation: Past, Present, and Future.Advanced materials technologies · 2022Article
- Imaging of photoacoustic-mediated permeabilization of giant unilamellar vesicles (GUVs).Scientific reports · 2021Article
- Controllable Cell Deformation Using Acoustic Streaming for Membrane Permeability Modulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Amphiphilic cationic cyclodextrin nanovesicles: a versatile cue for guiding cell adhesion.Nanoscale advances · 2020Article
- Cytosolic Delivery of Functional ProteinsACS applied materials & interfaces · 2020Article
- Acoustofluidic methods in cell analysis.Trends in analytical chemistry : TRAC · 2019Article
- Controlled and Tunable Loading and Release of Vesicles by Using Gigahertz Acoustics.Angewandte Chemie (International ed. in English) · 2019Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
Abstract
Controllable exchange of molecules between the interior and the external environment of vesicles is critical in drug delivery and micro/nano-reactors. While many approaches exist to trigger release from vesicles, controlled loading remains a challenge. Herein, we show that gigahertz acoustic streaming generated by a nanoelectromechanical resonator can control the loading and release of cargo into and from vesicles. Polymer-shelled vesicles showed loading and release of molecules both in solution and on a solid substrate. We observed deformation of individual giant unilamellar vesicles and propose that the shear stress generated by gigahertz acoustic streaming induces the formation of transient nanopores, with diameters on the order of 100 nm, in the vesicle membranes. This provides a non-invasive method to control material exchange across membranes of different types of vesicles, which could allow site-specific release of therapeutics and controlled loading into cells, as well as tunable microreactors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.