Evidence map›Paper›PMID 30417344›Full record

ArticleJournal of anatomy2019

Fascia thickness, aging and flexibility: is there an association?

Jan Wilke, Veronica Macchi, Raffaele De Caro, Carla Stecco

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of anatomy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06950541 (The Impact of Myofascial Therapy on Connective Tissue), which is not on this map. Cited by 73 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 3 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06950541 nacompletednot on this mapstarted 2023, after this paper: background citation

The Impact of Myofascial Therapy on Connective Tissue

TypeinterventionalSponsorJózef Piłsudski University of Physical EducationRan2023 to 2024Enrolled295ConditionsPainful, Fascial Manipulation, Fascia, PainArmsMyofascial therapy, Deep Tissue Massage
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 3 syntheses or guidelines pooled it, 140 citations in OpenAlex.

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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jan WilkeDepartment of Sports Medicine, Goethe University, Frankfurt, Germany.ORCID 0000-0001-9147-2369
Veronica MacchiDepartment of Molecular Medicine, Institute of Human Anatomy, University of Padova, Padova, Italy.
Raffaele De CaroDepartment of Molecular Medicine, Institute of Human Anatomy, University of Padova, Padova, Italy.
Carla SteccoDepartment of Molecular Medicine, Institute of Human Anatomy, University of Padova, Padova, Italy.
University of Padua · ITGoethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The morphology of the connective tissue may play an important role in locomotor mechanics. Recent research has revealed an association between increased fascia thickness and reduced joint flexibility in patients with chronic pain. The present study aimed to examine the relationship of both factors in healthy individuals, additionally testing the hypothesis that older subjects display a higher fascia thickness. Young (n = 18, 22 ± 1 years) and old (n = 17, 69 ± 4 years) healthy females were recruited for a quasi-experimental, cross-sectional trial. All participants underwent standardized ultrasound-based thickness measurements of the deep fasciae of the trunk and lower limb. Flexibility was assessed using sit and reach testing (hamstring extensibility) and the Schober test (lumbar flexion and extension). Systematic between-group differences of fascia thickness and variable associations (i.e. fascia thickness and flexibility) were detected using non-parametric data analyses. Young adults exhibited higher fascia thickness of the anterior and posterior lower leg, anterior thigh and abdominal wall (+12.3-25.8%, P < 0.05). Conversely, older participants showed higher thickness in the lumbar spine (+40.0-76.7%, P < 0.05). Correlations of both body mass and fascia thickness (τ = 0.45-0.75, P < 0.05), as well as flexibility and fascia thickness (τ = 0.38-0.42, P < 0.05) were found. Age-related changes in fascia thickness may be a contributing factor of restrictions in joint range of motion. Further study delineating the cause-effect triangle of body mass index, flexibility and fascia thickness is necessary.

Indexed as

AgedAgingCross-Sectional StudiesFasciaFemaleHumansMaleOrgan SizeRange of Motion, ArticularYoung Adultconnective tissuehyaluronic acidmyofascialstiffness

Identifiers

PMID30417344
PMCPMC6284431
OpenAlexW2901126772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.