Evidence map›Paper›PMID 30417341›Full record

ArticleHealth services research2019

Guideline-concordant initiation of oral anticoagulant therapy for stroke prevention in older veterans with atrial fibrillation eligible for Medicare Part D.

Nicolae Done, Amanda M Roy, Yingzhe Yuan, Steven D Pizer, Adam J Rose, Julia C Prentice

Open access · greenAbstract read
In one paragraph

Article in Health services research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. [Advances in anticoagulant therapy for cirrhosis combined with atrial fibrillation].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Nicolae DoneDepartment of Veterans Affairs, Center for Access Policy, Evaluation, and Research, Boston University School of Medicine, Boston, Massachusetts.ORCID 0000-0001-6517-646X
Amanda M RoyBouvé College of Health Sciences, Northeastern University, Boston, Massachusetts.
Yingzhe YuanVA Boston Healthcare System Research & Development, Partnered Evidence-Based Policy Resource Center, Northeastern University, Boston, Massachusetts.
Steven D PizerVA Boston Healthcare System Research & Development, Partnered Evidence-Based Policy Resource Center, Boston University School of Public Health, Boston, Massachusetts.ORCID 0000-0003-4908-5976
Adam J RoseBedford VA Medical Center, Center for Health Quality, Outcomes and Economic Research, Boston University School of Medicine, Boston, Massachusetts.ORCID 0000-0001-8681-6155
Julia C PrenticeDepartment of Veterans Affairs, Center for Access Policy, Evaluation, and Research, Boston University School of Medicine, Boston, Massachusetts.
Boston University · USNortheastern University · USBedford VA Research Corporation · US

Funding

Health Services Research and Development IIR 15-139
6 · The paper itself

Abstract

objectiveTo characterize the rate of guideline-concordant initiation of oral anticoagulation (OAC) among elderly Veterans with atrial fibrillation (AF) and high stroke risk. DATA SOURCES/STUDY

settingVeterans Health Administration (VHA) Corporate Data Warehouse (CDW) linked with Medicare claims 2011-2015. STUDY

designWe identified 6619 elderly, high stroke-risk patients with a new episode of AF initially diagnosed in the VHA during fiscal years 2012-2015. We used logistic regression to estimate marginal effects of associations between patient characteristics and OAC initiation within 90 days of the first AF episode. DATA EXTRACTION

methodsWe identified OACs using generic drug names. We calculated comorbidities and risk scores using diagnosis codes from 1 year of baseline data. PRINCIPAL

findingsOverall, 66.5% of Medicare-eligible Veterans with AF at high risk of stroke initiated an OAC within 90 days. We found lower initiation rates for patients enrolled in Medicare Part D and those ineligible for drug co-payment subsidies. OAC initiation rates increased during the study among VHA-reliant patients but not among dual VHA-Part D enrollees.

conclusionsOne-third of elderly Veterans at risk of stroke are not receiving recommended therapy. Increased coordination between Medicare and VHA providers may lead to improvements in anticoagulation quality and stroke prevention.

Indexed as

Medicare Part DAdministration, OralAgedAged, 80 and overAnticoagulantsAtrial FibrillationFemaleHumansHypertensionMaleStrokeUnited StatesUnited States Department of Veterans AffairsVeteransAnticoagulantschronic diseasemedical decision-makingpharmaceuticals: prescribing/use/costsVA Health Care System

Identifiers

PMID30417341
PMCPMC6338291
OpenAlexW2901859856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.