Evidence map›Paper›PMID 30417316›Full record

ArticleEJNMMI physics2018

A deep learning approach for

Fang Liu, Hyungseok Jang, Richard Kijowski, Gengyan Zhao, Tyler Bradshaw, Alan B McMillan

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 131 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Beyond CT: Attenuation correction for stand-alone brain PET.Zeitschrift fur medizinische Physik · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. A retrospective comparison of [Physical and engineering sciences in medicine · 2025
    Article
  13. Review
  14. Optimizing Attenuation Correction inDiagnostics (Basel, Switzerland) · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. ImprovingJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  19. Review
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fang LiuDepartments of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53705-2275, USA. leoliuf@gmail.com.ORCID http://orcid.org/0000-0001-8032-6681
Hyungseok JangDepartments of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53705-2275, USA.
Richard KijowskiDepartments of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53705-2275, USA.
Gengyan ZhaoMedical Physics, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53705-2275, USA.
Tyler BradshawDepartments of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53705-2275, USA.
Alan B McMillanDepartments of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI, 53705-2275, USA.
University of Wisconsin–Madison · US

Funding

Quantitative Oncologic PET-MRR01CA165221 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2012 to 2023
$4.7M
Improved Techniques for Substitute CT Generation from MRI datasetsR01EB026708 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI MCMILLAN, ALAN BLAIR · 2018 to 2021
$1.8M
Multi-component T2 and T2* mapping of All Water Components of Articular CartilageR01AR068373 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI KIJOWSKI, RICHARD · 2015 to 2018
$1.4M
NCI NIH HHS R01 CA165221NIAMS NIH HHS R01 AR068373NIBIB NIH HHS R01 EB026708
6 · The paper itself

Abstract

backgroundTo develop and evaluate the feasibility of a data-driven deep learning approach (deepAC) for positron-emission tomography (PET) image attenuation correction without anatomical imaging. A PET attenuation correction pipeline was developed utilizing deep learning to generate continuously valued pseudo-computed tomography (CT) images from uncorrected

resultsdeepAC produced pseudo-CTs with Dice coefficients of 0.80 ± 0.02 for air, 0.94 ± 0.01 for soft tissue, and 0.75 ± 0.03 for bone and MAE of 111 ± 16 HU relative to the PET/CT dataset. deepAC provides quantitatively accurate

conclusionsWe have developed an automated approach (deepAC) that allows generation of a continuously valued pseudo-CT from a single

Indexed as

Attenuation correctionCTDeep learningMRIPETPET/CTPET/MR

Identifiers

PMID30417316
PMCPMC6230542
OpenAlexW2885906943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.