ArticleEuropean journal of epidemiology2019
Association between physical activity and sub-types of cardiovascular disease death causes in a general population cohort.
Article in European journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Non-occupational physical activity and risk of cardiovascular disease, cancer and mortality outcomes: a dose-response meta-analysis of large prospective studies.British journal of sports medicine · 2023Pooled it
- Physical activity and the risk of heart failure: a systematic review and dose-response meta-analysis of prospective studies.European journal of epidemiology · 2021Pooled it
- Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies.Scientific reports · 2020Pooled it
- Physical activity and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies.BMC cardiovascular disorders · 2020Pooled it
- Cardiovascular Disease Knowledge Amongst Jordanian Population: A Cross-Sectional Study.Health science reports · 2026Article
- Daily Walking and Mortality in Racially and Socioeconomically Diverse U.S. Adults.American journal of preventive medicine · 2025Article
- Observational cohort study on physical activity patterns and coronary artery calcification among middle-aged adults.Bioinformation · 2025Article
- Association of sedentary behavior and physical activity with occurrence of signs and symptoms in participants of a cardiac rehabilitation program.Scientific reports · 2024Article
- Exposure-response associations between chronic exposure to fine particulate matter and risks of hospital admission for major cardiovascular diseases: population based cohort study.BMJ (Clinical research ed.) · 2024Article
- Association between Nontraditional Risk Factors and Calculated 10-Year Risk of Atherosclerotic Cardiovascular Disease in a Large General Population: Based on the Pars Cohort Study.The journal of Tehran Heart Center · 2023Article
- Personal Activity Intelligence and Ischemic Heart Disease in a Healthy Population: China Kadoorie Biobank Study.Journal of clinical medicine · 2022Article
- Causal Association of Cardiovascular Risk Factors and Lifestyle Behaviors With Peripheral Artery Disease: A Mendelian Randomization Approach.Journal of the American Heart Association · 2022Article
- Effects of exertional dyspnea on early mobilization of patients with acute decompensated heart failure.Journal of physical therapy science · 2022Article
- Prevention and Treatment of Cardiovascular Diseases with Plant Phytochemicals: A Review.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Burden of Aortic Aneurysm and Its Attributable Risk Factors from 1990 to 2019: An Analysis of the Global Burden of Disease Study 2019.Frontiers in cardiovascular medicine · 2022Article
- Encoder-Decoder Architecture for Ultrasound IMC Segmentation and cIMT Measurement.Sensors (Basel, Switzerland) · 2021Article
- Mechanisms of Dietary Sodium-Induced Impairments in Endothelial Function and Potential Countermeasures.Nutrients · 2021Review
- Association of level of leisure-time physical activity with risks of all-cause mortality and cardiovascular disease in an elderly Chinese population: a prospective cohort study.Journal of geriatric cardiology : JGC · 2020Article
- Exploring the association of long noncoding RNA expression profiles with intracranial aneurysms, based on sequencing and related bioinformatics analysis.BMC medical genomics · 2020Article
- Objectives, design and main findings until 2020 from the Rotterdam Study.European journal of epidemiology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physical activity is thought to be cardioprotective, but associations with different subtypes of cardiovascular disease (CVD) are poorly understood. We examined associations between physical activity and seven major CVD death causes. The sample comprised 65,093 adults (aged 58 ± 12 years, 45.4% men) followed up over mean [SD] 9.4 ± 4.5 years, recruited from The Health Survey for England and the Scottish Health Surveys. A CVD diagnosis was reported in 9.2% of the sample at baseline. Physical activity was self-reported. Outcomes were subtypes of CVD death; acute myocardial infarction; chronic ischaemic heart disease; pulmonary heart disease; a composite of cardiac arrest, arrhythmias, and sudden cardiac death; heart failure; cerebrovascular; composite of aortic aneurysm and other peripheral vascular diseases. There were 3050 CVD deaths (30.8% of all deaths). In Cox proportional hazards models adjusted for confounders, physical activity was associated with reduced relative risk of all CVD outcomes; compared with the lowest, the highest physical activity quintile was associated with reduced risk of acute myocardial infarction (Hazard ratio 0.66: 95% CI 0.50, 0.89), chronic ischaemic heart disease (0.49: 0.38, 0.64), pulmonary heart disease (0.48: 0.22, 1.07), arrhythmias (0.18: 0.04, 0.76); heart failure (0.35: 0.20, 0.63), cerebrovascular events (0.53: 0.38, 0.75); aneurysm and peripheral vascular diseases (0.54: 0.34, 0.93). Results were largely consistent across participants with and without existing CVD at baseline. Physical activity was associated with reduced risk of seven major CVD death causes. Protective benefits were apparent even at levels of activity below the current recommendations.
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Registered trials
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