ArticleAPL bioengineering2017
Transmural remodeling of right ventricular myocardium in response to pulmonary arterial hypertension.
Article in APL bioengineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 55 citations in OpenAlex.
- Ovarian hormones attenuate right ventricular remodeling in a rat model of pulmonary arterial hypertension.Biomechanics and modeling in mechanobiology · 2025Article
- Right Heart Failure in Critical and Chronic Care: Current Concepts, Challenges and Mechanical Support Strategies.Medical sciences (Basel, Switzerland) · 2025Review
- Left ventricular pressure-loading improves pressure-induced right ventricular remodeling by redistributing mechanical load and reducing mechanosignaling.Physiological reports · 2025Article
- Dissecting contributions of pulmonary arterial remodeling to right ventricular afterload in pulmonary hypertension.Bioengineering & translational medicine · 2025Article
- Right Ventricular Stiffening and Anisotropy Alterations in Pulmonary Hypertension: Mechanisms and Relations to Right Heart Failure.Journal of the American Heart Association · 2025Article
- Simulated Effects of Acute Left Ventricular Myocardial Infarction on Mitral Regurgitation in an Ovine Model.Journal of biomechanical engineering · 2024Article
- Establishment of a Biaxial Testing System for Characterization of Right Ventricle Viscoelasticity Under Physiological Loadings.Cardiovascular engineering and technology · 2024Article
- An image-driven micromechanical approach to characterize multiscale remodeling in infarcted myocardium.Acta biomaterialia · 2024Article
- A computational study of right ventricular mechanics in a rat model of pulmonary arterial hypertension.Frontiers in physiology · 2024Article
- Untangling the mechanisms of pulmonary arterial hypertension-induced right ventricular stiffening in a large animal model.Acta biomaterialia · 2023Article
- Characterizing the Spatiotemporal Transcriptomic Response of the Right Ventricle to Acute Pressure Overload.International journal of molecular sciences · 2023Article
- A multi-scale computational model for the passive mechanical behavior of right ventricular myocardium.Journal of the mechanical behavior of biomedical materials · 2023Article
- On the possibility of estimating myocardial fiber architecture from cardiac strains.Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH (Conference) · 2023Article
- Recent Advances in Tissue-Engineered Cardiac Scaffolds-The Progress and Gap in Mimicking Native Myocardium Mechanical Behaviors.Journal of functional biomaterials · 2023Review
- Untangling the mechanisms of pulmonary hypertension-induced right ventricular stiffening in a large animal model.bioRxiv : the preprint server for biology · 2023Article
- Improved right ventricular strain estimation in rats using anisotropic diffusion filtering.Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
- Right Ventricular Architectural Remodeling and Functional Adaptation in Pulmonary Hypertension.Circulation. Heart failure · 2023Article
- Alterations of biaxial viscoelastic properties of the right ventricle in pulmonary hypertension development in rest and acute stress conditions.Frontiers in bioengineering and biotechnology · 2023Article
- Simulation of the 3D Hyperelastic Behavior of Ventricular Myocardium using a Finite-Element Based Neural-Network Approach.Computer methods in applied mechanics and engineering · 2022Article
- Multiscale Contrasts Between the Right and Left Ventricle Biomechanics in Healthy Adult Sheep and Translational Implications.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Pulmonary arterial hypertension (PAH) imposes substantial pressure overload on the right ventricular free wall (RVFW), leading to myofiber hypertrophy and remodeling of its collagen fiber architecture. The transmural nature of these adaptations and their effects on the macroscopic mechanical behavior of the RVFW remain largely unexplored. In the present work, we extended our constitutive model for RVFW myocardium to investigate the transmural mechanical and structural remodeling post-PAH. Recent murine experimental studies provided us with comprehensive histomorphological and biaxial mechanical data for viable, passive myocardium for normal and post hypertensive cases. Multiple fiber-level remodeling events were found to be
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.