ArticleIEEE transactions on radiation and plasma medical sciences2018
Optimization of Energy Combination for Gold-based Contrast Agents below K-edges in Dual-energy Micro-CT.
Article in IEEE transactions on radiation and plasma medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Shock index as a predictor for mortality in trauma patients: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Pooled it
- Dual-Head Pix2Pix Network for Material Decomposition of Conventional CT Projections with Photon-Counting Guidance.Sensors (Basel, Switzerland) · 2025Article
- Spectral Photon Counting CT: Imaging Algorithms and Performance Assessment.IEEE transactions on radiation and plasma medical sciences · 2021Article
- Adaptive Nonlocal Means Method for Denoising Basis Material Images From Dual-Energy Computed Tomography.Journal of computer assisted tomographyArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Dual-energy micro-Computed Tomography provides high resolution non-invasive images at low cost. It can determine the concentrations of component materials in a mixture. Taking the advantages of K-edge, the gold-based agents contribute to improve the contrast of some physiological tissues with low natural contrast. Because the K-edge of gold (80.7 kVp) is excessively high, the anatomical structures could not be identified clearly in in vivo small animal experiments. In this study, the energy combination below K-edge is optimized to differentiate bone, soft tissue and gold. Furthermore, we evaluate the effects of concentration of contrast agents, the extrinsic filtration setting and dose level. Based on the quantitative analysis results of material decomposition, the optimized energy pair gathered in a certain range where the low-energy is 30kVp-40kVp. Our results can provide a practical guidance for the design of in vivo small animal experiments using gold-based contrast agents.
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