Evidence map›Paper›PMID 30417139›Full record

ArticleSynthetic and systems biotechnology2018

Nocardiopsistins A-C: New angucyclines with anti-MRSA activity isolated from a marine sponge-derived

Dongbo Xu, Keshav K Nepal, Jing Chen, Dedra Harmody, Haining Zhu, Peter J McCarthy, Amy E Wright, Guojun Wang

Abstract read
In one paragraph

Article in Synthetic and systems biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Identification of four novelInternational journal of systematic and evolutionary microbiology · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. GenusMarine drugs · 2022
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Antimicrobial compounds from marine actinomycetes.Archives of pharmacal research · 2020
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dongbo XuHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US 1 North, Fort Pierce, FL, 34946, United States.
Keshav K NepalHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US 1 North, Fort Pierce, FL, 34946, United States.
Jing ChenDepartment of Molecular and Cellular Biochemistry, University of Kentucky, 741 South Limestone, Lexington, KY, 40536, United States.
Dedra HarmodyHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US 1 North, Fort Pierce, FL, 34946, United States.
Haining ZhuDepartment of Molecular and Cellular Biochemistry, University of Kentucky, 741 South Limestone, Lexington, KY, 40536, United States.
Peter J McCarthyHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US 1 North, Fort Pierce, FL, 34946, United States.
Amy E WrightHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US 1 North, Fort Pierce, FL, 34946, United States.
Guojun WangHarbor Branch Oceanographic Institute, Florida Atlantic University, 5600 US 1 North, Fort Pierce, FL, 34946, United States.

Funding

Identifying the biosynthesis of a potent cytotoxic agent Lasonolide AR21CA209189 · NCI · FLORIDA ATLANTIC UNIVERSITY · PI WANG, GUOJUN · 2016 to 2017
$384k
NCI NIH HHS R21 CA209189
6 · The paper itself

Abstract

Marine natural products have become an increasingly important source of new drug leads during recent years. In an attempt to identify novel anti-microbial natural products by bioprospecting deep-sea Actinobacteria, three new angucyclines, nocardiopsistins A-C, were isolated from

Indexed as

ActinobacteriaAngucyclineAnti-MRSALaCl3NocardiopsisNocardiopsistins

Identifiers

PMID30417139
PMCPMC6223224

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.