ArticleCommunications biology2018
APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R.
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Article in Communications biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 3% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection.Communications biology · 2021Pooled it
- Codon Optimality Modulates Cellular Stress and Innate Immune Responses Triggered by Exogenous RNAs.Journal of molecular biology · 2026Article
- APOL1 kidney disease: a critical narrative review of molecular mechanisms, clinical heterogeneity, and the emerging therapeutic landscape.International urology and nephrology · 2026Review
- Impact of Apolipoprotein L1-Associated Pregnancy Complications on Kidney Disease Phenotypes in a HIV-Associated Nephropathy Mouse Model.Kidney360 · 2026Article
- Molecular mechanisms in podocytopathies: finding suitable targets for a new era of glomerular gene therapy.Clinical kidney journal · 2026Review
- APOL1-mediated kidney disease: a narrative review of the lessons learnt from the past 15 years.BMC nephrology · 2025Review
- APOL1 kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.Kidney international · 2025Article
- Apolipoprotein-L1 G1 variant contributes to hydrocephalus but not to atherosclerosis in apolipoprotein-E knock-out mice.Clinical science (London, England : 1979) · 2025Article
- Interferon Upregulation Associates with Insulin Resistance in Humans.Current diabetes reviews · 2025Review
- Pathogenesis of HIV-associated nephropathy in children and adolescents: taking a hard look 40 years later in the era of gene-environment interactions.American journal of physiology. Renal physiology · 2024Review
- PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy.eLife · 2024Article
- Preeclampsia in mice carrying fetuses with APOL1 risk variants.bioRxiv : the preprint server for biology · 2024Article
- Type I IFN in Glomerular Disease: Scarring beyond the STING.International journal of molecular sciences · 2024Review
- Apolipoprotein L1 (APOL1) renal risk variant-mediated podocyte cytotoxicity depends on African haplotype and surface expression.Scientific reports · 2024Article
- APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease.The Journal of clinical investigation · 2024Article
- PPIB/Cyclophilin B expression associates with tumor progression and unfavorable survival in patients with pulmonary adenocarcinoma.American journal of cancer research · 2024Article
- APOL1-G2 accelerates nephrocyte cell death by inhibiting the autophagy pathway.Disease models & mechanisms · 2023Article
- A SNARE protective pool antagonizes APOL1 renal toxicity in Drosophila nephrocytes.Cell & bioscience · 2023Article
- Novel Therapies inKidney international reports · 2023Review
- The metabolic effects of APOL1 in humans.Pflugers Archiv : European journal of physiology · 2023Review
Corrections and comments
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Authors and funding
19 authors at 9 institutions in 2 countries.
Koji OkamotoKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, USA.
Jason W RauschReverse Transcriptase Biochemistry Section, Basic Research Program, Frederick National Laboratory for Cancer Research, 1050 Boyle Street, Frederick, MD, 21702, USA.
Hidefumi WakashinKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, USA.
Yulong FuChildren's National Health System, 111 Michigan Ave NW, Washington, DC, 20010, USA.
Joon-Yong ChungExperimental Pathology Lab, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0001-5041-5982
Patrick D DummerKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, USA.
Myung K ShinMerck Research Laboratories, Merck and Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ, 07033, USA.
Preeti ChandraDivision of Nephrology, Department of Medicine, University of Maryland School of Medicine, 655 W. Baltimore Street, Baltimore, MD, 21201, USA.
Kosuke SuzukiDivision of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.
Shashi ShrivastavKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, USA.
Avi Z RosenbergDepartment of Pathology, Johns Hopkins Medical Institutions, 720 Rutland Avenue, Baltimore, MD, 21287, USA.
Stephen M HewittExperimental Pathology Lab, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0001-8283-1788
Patricio E RayChildren's National Health System, 111 Michigan Ave NW, Washington, DC, 20010, USA.
Eisei NoiriDepartment of Nephrology, Endocrinology, Hemodialysis & Apheresis, University Hospital, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 133-8655, Japan.
Stuart F J Le GriceReverse Transcriptase Biochemistry Section, Basic Research Program, Frederick National Laboratory for Cancer Research, 1050 Boyle Street, Frederick, MD, 21702, USA.
Maarten HoekMerck Research Laboratories, Merck and Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ, 07033, USA.
Zhe HanChildren's National Health System, 111 Michigan Ave NW, Washington, DC, 20010, USA.
Cheryl A WinklerBasic Research Laboratory, Center for Cancer Research, National Cancer Institute, Leidos Biomedical Research, Frederick National Laboratory, 8560 Progress Dr., Frederick, MD, 21702, USA.ORCID http://orcid.org/0000-0001-5552-0917
Jeffrey B KoppKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, USA. jbkopp@nih.gov.
National Institutes of Health · USChildren's National · USFrederick National Laboratory for Cancer Research · USMerck & Co., Inc., Rahway, NJ, USA (United States) · USJohns Hopkins University · USLeidos (United States) · USTohoku University Hospital · JPUniversity of Maryland, Baltimore · USUniversity of Tokyo Hospital · JP
Funding
Focal Segmental Glomerulosclerosis: Genetics & MechanismsZIADK043308 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KOPP, JEFFREY BURNETT · 2009 to 2024
$15.7MNucleic Acid Footprinting and development of small molecule antagonistsZIABC010493 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LE GRICE, STUART F. J. · 2009 to 2021
$9.3MFocal segmental glomerulosclerosis: TreatmentZIADK043412 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KOPP, JEFFREY BURNETT · 2009 to 2024
$7.4MModeling Nephrotic Syndrome in Drosophila NephrocytesR01DK098410 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI HAN, ZHE · 2014 to 2022
$3.3MRole of cytokines and APOL-1 in the pathogenesis of childhood HIV associated nephrologyR01DK103564 · NIDDK · UNIVERSITY OF VIRGINIA · PI RAY, PATRICIO E. · 2014 to 2023
$3.0MNovel mechanisms and Drosophila model of APOL1-HIV-1 nephropathies in childrenR01DK115968 · NIDDK · UNIVERSITY OF VIRGINIA · PI HAN, ZHE, RAY, PATRICIO E. · 2018 to 2022
$2.3MPathogenesis of chronic renal injury and hypertension in HIV-infected childrenR01DK108368 · NIDDK · UNIVERSITY OF VIRGINIA · PI RAY, PATRICIO E. · 2015 to 2019
$1.5MNIDDK NIH HHS R01 DK098410NIDDK NIH HHS R01 DK103564NIDDK NIH HHS R01 DK108368NIDDK NIH HHS R01 DK115968
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