Evidence map›Paper›PMID 30416940›Full record

ReviewCurrent pharmacology reports2018

Redox Modulation at Work: Natural Phytoprotective Polysulfanes From

Awais Anwar, Emma Gould, Ryan Tinson, Javaid Iqbal, Chris Hamilton

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current pharmacology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. The Disulfide Stress Response and ProteinAntioxidants (Basel, Switzerland) · 2019
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Awais AnwarEcospray Limited, Grange Farm, Hilborough, Thetford, Norfolk, IP26 5BT UK.
Emma Gould2School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ UK.
Ryan Tinson2School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ UK.
Javaid Iqbal3Department of Plant Protection, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Chris Hamilton2School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ UK.
Norwich Research Park · GBUniversity of East Anglia · GBKing Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis article provides a brief overview of natural phytoprotective products of RECENT

findingsThe article finds polysulfanes potentials as new generation novel antibiotics and chemo preventive agent. The effective dose rates of polysulfanes for antimicrobial properties are in the range of 0.5-40 mg/L and for anticancer 20-100 μM. The molecular targets for these redox modulators are mainly cellular thiols as well as inhibition and/or activation of certain cellular proteins in cancer cell lines. SUMMARY: Antimicrobial and anticancer activities of polysulfanes published in the literature indicate that with further development, they could be promising candidates for cancer prevention due to their selectivity towards abnormal cells.

Indexed as

Allium sativumChemo-preventionGarlicGlutathionePolysulfanesReactive sulfur speciesRedox modulators

Identifiers

PMID30416940
PMCPMC6208768
OpenAlexW2891909326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.