Evidence map›Paper›PMID 30416852›Full record

ArticleAmerican journal of cancer research2018

Novel nano-drug combination therapeutic regimen demonstrates significant efficacy in the transgenic mouse model of pancreatic ductal adenocarcinoma.

Arvind Thakkar, Preshita Desai, Sushma Chenreddy, Jalpa Modi, Astrid Thio, Wael Khamas, David Ann, Jeffrey Wang, Sunil Prabhu

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  6. Review
  7. Nanotechnology-Assisted Cell Tracking.Nanomaterials (Basel, Switzerland) · 2022
    Review
  8. Review
  9. Review
  10. Review
  11. Is Curcumin the Answer to Future Chemotherapy Cocktail?Molecules (Basel, Switzerland) · 2021
    Review
  12. Frontiers in cell and developmental biology · 2021
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Arvind ThakkarDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences 309 E. 2nd Street, Pomona, CA 91766, USA.
Preshita DesaiDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences 309 E. 2nd Street, Pomona, CA 91766, USA.
Sushma ChenreddyDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences 309 E. 2nd Street, Pomona, CA 91766, USA.
Jalpa ModiDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences 309 E. 2nd Street, Pomona, CA 91766, USA.
Astrid ThioDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences 309 E. 2nd Street, Pomona, CA 91766, USA.
Wael KhamasCollege of Veterinary Medicine, Western University of Health Sciences 309 E. 2nd Street, Pomona, CA 91766, USA.
David AnnDepartment of Diabetes and Metabolic Diseases Research, Beckman Research Institute City of Hope, Duarte, CA 91010, USA.
Jeffrey WangDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences 309 E. 2nd Street, Pomona, CA 91766, USA.
Sunil PrabhuDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences 309 E. 2nd Street, Pomona, CA 91766, USA.
Western University of Health Sciences · USCity of Hope · USNew England College · US

Funding

Combinatorial nanotechnology-based regimens for pancreatic cancer chemopreventionR15CA182834 · NCI · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI PRABHU, SUNIL · 2014 to 2014
$438k
NCI NIH HHS R15 CA182834
6 · The paper itself

Abstract

The current work studied the chemopreventive efficacy of orally administered chitosan coated solid-lipid nanoparticle (c-SLN) encapsulated aspirin (ASP), curcumin (CUR) and free sulforaphane (SFN), ACS-cSLN, in the

Indexed as

Chemopreventionchitosan-solid lipid nanoparticles (c-SLNs)oncogenic KRaspancreatic ductal adenocarcinoma (PDAC)transgenic mice

Identifiers

PMID30416852
PMCPMC6220149
OpenAlexW2986018097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.